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has been cited by the following article:

• TITLE: Some Marker Enzymes and Histological Alteration on the Administration of Tramadol Hydrochloride on Rat Liver

  AUTHORS: George Gborienemi Simeon, Silas Tonye Abbey

  KEYWORDS: Marker Enzymes, Histological, Alteration, Tramadol

  JOURNAL NAME: Modern Research in Inflammation, Vol.7 No.1, February 6, 2018

  ABSTRACT: The ease of availability and potential tendency to abuse tramadol hydrochloride prompted this research. Making use of biochemical and histological techniques, concentrations of marker enzymes were monitored along with alterations in the liver architecture of wistar albino rats in graded doses of tramadol hydrochloride for 28 days. Specifically, levels of gammaglutamyltransferase (-GT), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined. Statistical evaluation of the results at a p