TITLE:
Outcomes of Surgical Treatment of Skin Cancer at Surgical Oncology Unit of Donka, Conakry University Hospital
AUTHORS:
Bangaly Traore, Leopold Lamah
KEYWORDS:
Skin Cancer, Surgery, Prognosis
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.8 No.12,
December
4,
2017
ABSTRACT: Aim: The main aim of this study was to evaluate outcomes after surgical
treatment of skin cancer. Methods: This retrospective cohort study
concerned 46 patients who presented 43 skin cancers lesions surgically treated
at surgical oncology unit, Conakry University Hospital. There were 29 (61.7%)
squamous cell carcinoma, 12 (25.5%) melanoma, 4 (8.5%) sarcomas and 1 (2.1%)
porocarcinoma. Surgical indications and prognosis factors were analyzed. Results:
Surgical treatment included simple excision in 2 cases (3.8%), wide excision in
38 cases (71.7%) and amputation/disarticulation in 13 cases (24.5%). Inguinal
lymph node dissection was performed in 16 patients (34.3%). Postoperative
complications were wound suppuration (5 cases), lower limb lymphedema (4
cases), seroma (2 cases) and skin flap necrosis (1 case). Surgical margins were
free in 28 (60.9%) patients, infiltrated in 3 patients (6.5%) and unspecified
in 15 patients (32.6%). The median follow-up after surgery was 29 months.
During the follow-up, 13 patients (28.3%) had a relapse. The relapse was influenced
by surgical margins (p = 0.012) and
iterative resection (p = 0.04).
Overall survival was 65.2%. Factors related to survival in univariate analysis
were: iterative resection (p =
0.008), fungated tumor (p = 0.037),
the status of surgical margins (p =
0.002) and the occurrence of relapse (p = 0.0000). In multivariate
analysis, the status of surgical margins was the only independent prognostic
factor. Conclusion: The prognosis after surgical treatment of cutaneous
cancers depends on the resection margins.