TITLE:
Long-Term Survival after Resection for Primary Undifferentiated Pleomorphic Sarcoma of the Jejunum with Lymph Node Metastases: Case Report
AUTHORS:
Shigeru Fujisaki, Motoi Takashina, Kenichi Sakurai, Ryouichi Tomita, Tadatoshi Takayama
KEYWORDS:
Undifferentiated Pleomorphic Sarcoma, Jejunum, Metastatic Lymph Nodes
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.8 No.12,
December
4,
2017
ABSTRACT: Primary undifferentiated
pleomorphic sarcoma (UPS) of the small intestine is extremely rare. The
prognosis of UPS is basically poor, and particular, when accompanied with
metastatic lesions. This paper reports the case of a long-term survivor of
primary UPS of the jejunum with lymph node metastases and a skip lesion in the
jejunum. The patient was a 50-year-old Japanese man who presented with a chief
complaint of breathlessness. Small bowel X-ray series revealed an approximately
4-cm size with protruded lesion (image shows a filling defect) in the proximal
jejunum. Based on a presumptive diagnosis of the hemorrhagic small bowel tumor,
he underwent a laparotomy. A tumor was observed in the jejunum at approximately
90-cm from the Treitz ligament; some swollen mesenteric lymph nodules were also
observed. Segmental resection of the jejunum was performed 20-140 cm from the
Treitz ligament. A complete surgical excision with en-bloc regional lymph node
dissection was performed. The final histopathological diagnosis was UPS of the
jejunum with metastatic lymph nodes and a skip lesion in the jejunum. The
postoperative course was uneventful. The patient was not given adjuvant
chemotherapy and was discharged on postoperative day 16. He is currently well
without any evidence of recurrence for >10 years after the operation.