Tamaki, Y., Higa, F., Tasato, D., Nakamura, H., Uechi, K., Tamayose, M., Haranaga, S., Yara, S., Tateyama, M. and Fujita, J. (2011) Pneumocystis jirovecii Pneumonia and Alveolar Hemorrhage in a Pregnant Woman with Human T Cell Lymphotropic Virus Type-1 Infection. Internal Medicine, 50, 351-354.
https://doi.org/10.2169/internalmedicine.50.4482

has been cited by the following article:

• TITLE: A Human T Lymphotropic Virus Type 1 Carrier Coinfected with Mycobacterium intracellulare and Pneumocystis jirovecii with a Characteristic Compositional Change of Bone Marrow Cells

  AUTHORS: Sayaka Uda, Shinsuke Shiotsu, Ayaka Omura, Ryosuke Hamashima, Akihiro Yoshimura, Naoko Kurisu, Tomoya Sagawa, Koichi Hasegawa, Tatsuya Yuba, Chieko Takumi, Seiko Ono, Noriya Hiraoka, Noriya Hiraoka

  KEYWORDS: Human T Lymphotropic Virus Type 1, Carrier, Immunodeficiency, Pneumocystis jirovecii

  JOURNAL NAME: Open Journal of Respiratory Diseases, Vol.7 No.3, August 8, 2017

  ABSTRACT: Human T lymphotropic virus type 1 (HTLV-1) is endemic in the southern part of Japan. Infection of the virus can cause adult T cell leukemia/lymphoma (ATL), while most infected individuals remain in a carrier state for a long period of time. Although rare cases of carriers, like ATL patients, who developed opportunistic infections, have been reported, hematological changes of carriers who are prone to opportunistic infections have not been well defined. Here, we present a case of an HTLV-1 carrier who developed Mycobacterium intracellulare infection and Pneumocystis jirovecii pneumonia (PcP) simultaneously. Flow cytometric analysis of bone marrow cells revealed an aberrant compositional change similar to that in ATL patients. This suggests the presence of a pre-ATL state prior to the development of ATL, which is notable in terms of underlying cellular immunodeficiency.