Elwan, N.M., Abdelhadi, H.A. and Hassaneen, H.M. (1996) Synthesis of [1,2,4] triazolo [3,4-a] isoquinolines and pyrrolo [2,1-a] Isoquinolines using α-keto hydrazonoyl halides, Tetrahedron, 52, 3451-3456. doi:10.1016/0040-4020(96)00024-5

has been cited by the following article:

• TITLE: Reactivity of 1-methylisoquinoline synthesis of pyrazolyl triazoloisoquinoline and thia-diazolyl isoquinoline derivatives

  AUTHORS: Hamdi M Hassaneen, Huwaida M. E Hassaneen, Yasmin Sh Mohammed

  KEYWORDS: [1, 2, 4]Triazolo[3, 4-a]isoquinolines; Enaminones; Hydrazonoyl Halides; Cycloaddition Reactions; Chitosan; Thioanilides; [1, 3, 4]Thiadiazolylisoquinoline Derivatives

  JOURNAL NAME: Natural Science, Vol.3 No.8, August 3, 2011

  ABSTRACT: The reaction of 1-methylisoquinoline 1 with hy-drazonoyl halides 2 in ethanol in the presence of chitosan under microwave irradiation affords triazoloisoquinoline 4. Product 4 reacts with dimethylformamide-dimethylacetal to give ena- minones 7 which react with hydrazonoyl halides to give pyrazolyl triazoloisoquinoline 13. Also, 1-methylisoquinoline 1 reacts with arylisothio-cyanate to give thioanilide 15 which reacts with hydrazonoyl halides to give the corresponding thiadiazolyl isoquinoline derivatives 20, 24.