TITLE:
Variations of Hair Trace Element Contents in Diabetic Females
AUTHORS:
Saleh A. K. Saleh, Sameer H. Fatani, Heba M. Adly, Altaf A. Abdulkhaliq, Hiba S. Al-Amodi
KEYWORDS:
Hair, Trace Elements, Diabetes Mellitus, Women, Saudi Arabia
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.5 No.1,
January
24,
2017
ABSTRACT: Background: Alterations of trace elements, could induce metabolic disorders as they forthwith participating in the metabolic pathways and play different roles modulating it as well as many enzymes require trace elements for their activation and functions. Of these elements, selenium (Se), zinc (Zn), copper (Cu) and manganese (Mn) have been recognized as essentials for metabolism. Hyperglycemia and diabetes mellitus are important causes of mortality and morbidity worldwide, and their global prevalence are growing from 2.8% in 2000 projecting to be 4.4% in 2030. Diabetes is prevalent in Saudi Arabia with high incidence in urbanized areas and its prevalence is estimated to expand 3 times by 2030. Patients and Methods: In total, 75 diabetic women and 80 aberrantly healthy women were recruited. Clinical and familial history was recorded. Hair Se, Zn, Cu and Mn levels were analyzed as well as fasting blood sugar (FBS), glycated hemoglobin (HbA1c). Results: Our findings revealed a marked decrease of Zn and Mn levels in diabetic women hair compared to control group (p