Mamounas, E., Bandos, H., White, J., Julian, T., Khan, A., Shaitelman, S., Torres, M., Vicini, F., Ganz, P., McCloskey, S., Paik, S., Gupta, N., Li, X., DiCostanzo, D., Costantino, J., Curran, W. and Wolmark, N. (2016) Abstract OT2-02-02: NRG Oncology/NSABP B-51/RTOG 1304: A Phase III Clinical Trial to Determine If Chest Wall and Regional Nodal Radiotherapy (CWRNRT) Post Mastectomy (Mx) or the Addition of RNRT to Breast RT Post Breast-Conserving Surgery (BCS) Will Reduce Invasive Cancer Events in Patients (pts) with Positive Axillary (Ax) Nodes Who Are ypN0 after Neoadjuvant Chemotherapy (NC). Cancer Research, 76, OT2-02-02.
http://cancerres.aacrjournals.org/content/76/4_Supplement/OT2-02-02

has been cited by the following article:

• TITLE: Use of Three Dimensional Conformal Radiation Therapy for Node Positive Breast Cancer Does Not Result in Excess Lung and Heart Irradiation

  AUTHORS: Phillip Prior, Irina Sparks, J. Frank Wilson, Joseph Bovi, Adam Currey, Julie Bradley, Tracy Kelly, X. Allen Li, Julia R White

  KEYWORDS: Node Positive Breast Cancer, Dose-Volume Goals, Target Coverage, CT Based Planning

  JOURNAL NAME: International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, Vol.6 No.1, January 11, 2017

  ABSTRACT: Purpose: This work evaluates the use of target and organs at risk (OAR) dose-volume goals in 3D conformal radiotherapy (3DCRT) planning for node positive breast cancer (NPBC) patients undergoing regional nodal irradiation after lumpectomy/mastectomy. Methods: Dosimetric data for 262 NPBC patients receiving regional nodal and whole breast/chest wall (WB/CW) irradiation from 2000-2009 were analyzed. In all cases, target & OAR volumes were delineated on treatment CT scans for field generation and dose-volume histograms (DVHs) were generated. Cases were analyzed to identify how frequently they met treatment planning institutional dose-volume goals (“institutional guidelines” & standardized in 2005) and how this would affect OAR doses. Results: The incidence of cases from 2000-2009 meeting current institutional guidelines improved over the study period. Target coverage improved from 2005-2009, when guidelines were followed as a part of the plan approval. Those cases from 2000-2004 meeting acceptable target goals were found to be significantly different from those cases from 2005-2009 (p Conclusions: The use of institutional guidelines in 3DCRT for WB/CW and regional nodal irradiation for NPBC patients improved target coverage without a statistically significant increase in heart and lung doses.