Article citationsMore>>
Nathanson, E., Weezenbeek, C.L., Rich, M.L., Gupta, R., Bayona, J., Blöndal, K., Caminero, J.A., Cegielski, J.P., Danilovits, M., Espinal, M.A., Hollo, V., Jaramillo, E., Leimane, V., Mitnick, C.D., Mukherjee, J.S., Nunn, P., Pasechnikov, A., Tupasi, T., Wells, C. and Raviglione, M.C. (2006) Multidrug-Resistant Tuberculosis Management in Resource-Limited Settings. Emerging Infectious Diseases, 12, 1389-1397.
www.cdc.gov/eid
http://dx.doi.org/10.3201/eid1209.051618
has been cited by the following article:
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TITLE:
First-Line Drug Resistance Patterns of Mycobacterium tuberculosis Complex Isolates from Re-Treatment Patients from Sudan
AUTHORS:
Muatsim Ahmed Mohammed Adam, Hamdan Mustafa Hamdan Ali, Eltahir Awad Gasim Khalil
KEYWORDS:
MDR, Sudan, TB, Re-Treatment, DST
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.4 No.3,
August
18,
2016
ABSTRACT: Drug susceptibility testing (DST) plays a pivotal role in TB patients’ management leading to the selection of most effective drugs. This study aimed to determine resistance patterns to first line anti-TB drugs in Mycobacterium tuberculosis isolates from re-treated patients from Sudan. A total of 239 sputum specimens were collected from smear positive re-treatment TB patients during the period from July 2009 to July 2010. Specimens were pre-treated according to Petroff method. The recovered isolates were tested for sensitivity to first line anti-TB drugs by the 1% proportion method. One hundred and forty three (143/239, 59.8%) mycobacterial isolates were successfully recovered. The majority (98.6%, 141/143) of the isolates were Mycobacterium tuberculosis complex strains. Two strains (2/143, 1.4%) were identified as RIF/INH-resistant MOTT, while fifty four isolates (38.3%, 54/141) were MDR. Multi- drug resistant Mycobacterium tuberculosis complex (MDR-TB) among re-treatment patients from national referral centers for tuberculosis diagnosis and management was considerably high in the study isolates.
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