Jennings, L.D., Kincaid, S.L., Wang, Y.D., Krishnamurthy, G., Beyer, C.F., McGinnis, J.P., Miranda, M., Discafani, C.M. and Rabindran, S.K. (2005) Parallel Synthesis and Biological Evaluation of 5,6,7,8-Tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one Cytotoxic Agents Selective for p21-Deficient Cells. Bioorganic & Medicinal Chemistry Letters, 15, 4731-4735.
http://dx.doi.org/10.1016/j.bmcl.2005.07.072

has been cited by the following article:

• TITLE: Synthesis and Antitumor Activity of Novel Thienopyrimidine Derivatives Containing Thiosemicarbazide Moiety

  AUTHORS: Samir B. Salib, Omneya M. Khalil, Mona M. Kamel, Yara El-Dash

  KEYWORDS: Synthesis, Thieno[2, 3-d]Pyrimidine, Thiosemicarbazides, Anticancer Agents

  JOURNAL NAME: Open Access Library Journal, Vol.3 No.7, July 26, 2016

  ABSTRACT: The present study focused on synthesizing a series of novel derivatives of 4-aryl-1-[2-(3-benzyl-4-oxo(3H)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-ylsulphanyl) acetyl] thiosemicarbazide 5a-d and evaluating their antitumor activity. The structure of the synthesized compounds has been elucidated on the basis of elemental analyses and spectroscopic methods (IR, 1H-NMR, 13C-NMR and MS). The in vitro cytotoxic activity of the synthesized derivatives was evaluated against two human cell lines: prostate cancer (PC-3) and colon cancer (HCT-116).