TITLE:
Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats
AUTHORS:
O. A. Awoyinka, A. Ileola, C. N. Imeoria, A. E. Omonisi, F. C. Oladele, M. F. Asaolu
KEYWORDS:
Dextran Sodium Sulphate (DSS) Otili, Feregede, Pakala, Mucuna, Colon Cancer
JOURNAL NAME:
Open Access Library Journal,
Vol.3 No.7,
July
11,
2016
ABSTRACT:
This work is an investigation of the curative effects of some edible and
wild type beans on colonic inflammation induced by Dextran Sulphate Sodium
(DSS) in wister albino rats. Macroscopic examination performed on the colon
after seven-day exposure of the animals to both DSS and bean sample revealed a
high incidence of colonic inflammation in rats fed with macuna compared to other groups. However,
from the histological examination, the groups fed with Otili and Feregede had a low incidence of dysplasia showing Otili and Feregede to be
good candidates that could mitigate effect of Dextran Sodium Sulphate.