Burkovitz, A., Sela-Culang, I. and Ofran, Y. (2014) Large-Scale Analysis of Somatic Hypermutations in Antibodies Reveals Which Structural Regions, Positions and Amino Acids Are Modified to Improve Affinity. FEBS Journal, 281, 306-319.
http://dx.doi.org/10.1111/febs.12597

has been cited by the following article:

• TITLE: “Natural Site-Directed Mutagenesis” Might Exist in Eukaryotic Cells

  AUTHORS: Gao-De Li

  KEYWORDS: Natural Site-Directed Mutagenesis, Genetic Alteration, Mutation, CAGFs, DNA to DNA Transcription, Drug Resistance, Evolution of Eukaryotes, Antibody Diversity, Somatic Hypermutation

  JOURNAL NAME: Open Access Library Journal, Vol.3 No.4, April 18, 2016

  ABSTRACT: Site-directed mutagenesis refers to a man-made molecular biology method that is used to make genetic alterations in the DNA sequence of a gene of interest. But based on our recently published experimental findings, we propose that “natural site-directed mutagenesis” might exist in eukaryotic cells, which is triggered by harmful agents and co-directed by special transcription hotspots and mutation-contained intranuclear primers.