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http://dx.doi.org/10.1093/ije/dyp162

has been cited by the following article:

• TITLE: Effects of Obesity and Smoking on Survival in Non-Small Cell Lung Cancer

  AUTHORS: Damien M. Hansra, Tulay Koru-Sengul, Wei Zhao, Feng Miao, Alicia P. Monedero, Stacey L. Tannenbaum, David J. Lee, Judith Hurley, Margaret M. Byrne

  KEYWORDS: Lung Cancer, Non-Small Cell Lung Cancer, Tobacco, Smoking, Obesity

  JOURNAL NAME: Open Journal of Epidemiology, Vol.6 No.2, May 24, 2016

  ABSTRACT: Background: Obesity is an emerging leading cause of morbidity and mortality in the US and the relationship between obesity, tobacco, and survival in NSCLC is unclear. Methods: Data (n = 87,631) were obtained from linkage of the 1996-2007 Florida Cancer Data System to the Agency for Health Care Administration database providing procedure and diagnoses codes. Survival time was calculated from date of diagnosis to date of death. Smoking status was categorized as never, current, and former. Obesity (yes/no) = ICD9 code BMI > 30 kg/m2, cachexia = ICD9 code “wasting syndrome”, & non-obese = non-obese & non cachectic. Cox proportional regression models used to predict survival; demographic, clinical, treatment factors, & comorbidities were included in adjusted models with smoking status and obesity as the main factors. Results: The majority of patients (pts) were either former (49%) or current (40%) smokers, & non-obese (88%). 6.8% of pts were obese & 4.8% of pts were cachectic. There were significant differences between survival curves and median survival (months) for obese vs. non-obese vs. cachectic pts. (20 vs 10 vs. 7.9; P