TITLE:
The Endometrium Biopsy and Hystero-Laparoscopy in Evaluation of Women’s Infertility. A Prospective Study in Algeria
AUTHORS:
Nassima Cheheb, Abdenacer Tou, Fadl Allah Abou-Bekr, Mohammed Lebid
KEYWORDS:
Female Infertility, Endometrial Biopsy, Hystero-Laparoscopy
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.4,
March
18,
2016
ABSTRACT: Female infertility is considered as a real obstacle to the development of
a couple who cannot conceive in a natural way. The aim of this study is to
evaluate female infertility using two complementary methods of exploration:
hystero-laparoscopy and endometrial biopsy, to compare histopathological data
with those of hystero-laparoscopy findings in the same patients, and finally
assess the interest to couple both methods to detect a greater number of
pathologies. Our prospective study included 64 patients aged 20 - 43 years with
primary or secondary infertility for a period of 3 years ranging from 2012 to
2015 at obstetrics and gynecology department in which all patients were
admitted to a hysteroscopy followed by laparoscopy. Endometrial biopsy
curettage was performed and sent to the Pathological Anatomy Department for a
histopathological study. On 64 infertile women explored, no pathologies were
findings in 20 patients (31.3%) to the biopsy and 27 patients (42.2%) by
hysteroscopy-laparoscopy. Histopathological study was in favor of dysfunctional
endometrium (50%) followed by hyperplasia (10.9%). The lesions findings in the
hystero-laparoscopy were in the first place uterine (18.8%) followed by equally
between tubal and endometrial pathologies (10.9%). Associated diseases
affecting the same organs or more were recorded with a percentage of 7.8%. The
two methods have been shown effective and the most of common pathologies
findings were uterine and endometrial. We concluded that the endometrial biopsy
was more decisive in the exploration of endometrium pathologies while
hystero-laparoscopy is more sensitive for the exploration of uterine, tubal and
ovarian pathologies. Each method taken individually was revealed incomplete. It
is more interesting to systematically couple the histology with endoscopic
examination in order to detect a greater number of pathologies.