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Tomczuk, B.E., Taylor Jr., C.R., Moses, L.M., Sutherland, D.B., Lo, Y.S., Johnson, D.N., Kinnier, W.B. and Kilpatrick, B.F. (1991) 2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as Non-Benzodiazepine Anticonvulsants and Anxiolytics. Journal of Medicinal Chemistry, 34, 2993-3006.
http://dx.doi.org/10.1021/jm00114a007
has been cited by the following article:
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TITLE:
Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions
AUTHORS:
Azizollah Habibi, Yousef Valizadeh, Marjan Mollazadeh, Abdolali Alizadeh
KEYWORDS:
Benzimidazoles, Green Chemistry, Arylidene Malononitrile, 1, 2-Phenylenediamines
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.5 No.4,
December
9,
2015
ABSTRACT: A fast, high efficiency and environmentally friendly procedure for the synthesis of 2-aryl benzim-idazole derivatives has been reported. Reaction between 1,2-phenylenediamine derivatives and arylidene malononitrile under aqueous media and also solvent-free conditions generates 2-aryl benzimidazole derivatives with a high yield.