TITLE:
Evaluation of a Plasma hCG Method for Point of Care Testing with the Aim of Shortening Test-Turnaround-Times
AUTHORS:
Anna-Karin Wikström, Magnus Hagmar, Göran Ronquist, Anders Larsson
KEYWORDS:
Human Chorionic Gonadotropin, Pregnancy, Method Evaluation, Point of Care Test
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.5 No.6,
June
19,
2015
ABSTRACT: Objective: To examine the correlation between plasma hCG results obtained
with the new i-STAT® hCG point of care test with those concomitantly
obtained from the central hospital laboratory utilizing the same patient
samples. Methods: Prospective
cross-sectional laboratory test evaluation. We compared plasma hCG results
obtained with the i-STAT® hCG test (Abbott Point of Care, Princeton, NJ,
USA) with Architect Ci8200 (Abbott Laboratories, Abbott Park, IL, USA). We also
calculated the total coefficient of variation (CV) for the i-STAT® method.
Results: The two methods showed
a good linear correlation (R2 = 0.994; slope 1.03) and CV for the
i-STAT® method was 2.1% - 5.2%. Conclusion:
We suggest that the i-STAT® hCG blood assay could be used as a complement
to urine hCG assays in clinical situations when rapid test results are needed
and urine is not available.