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has been cited by the following article:

• TITLE: Cylindrospermopsin in Water Supply Reservoirs in Brazil Determined by Immunochemical and Molecular Methods

  AUTHORS: Maria do Carmo Bittencourt-Oliveira, Viviane Piccin-Santos, Paula Kujbida, Ariadne do Nascimento Moura

  KEYWORDS: Aphanizomenon, Cyanobacteria, Cylindrospermopsis Raciborskii, CYN, Sphaerospermopsis Aphanizomenoides, Toxin

  JOURNAL NAME: Journal of Water Resource and Protection, Vol.3 No.6, July 5, 2011

  ABSTRACT: It is reported for the first time in Brazil and South America the presence of cylindrospermopsin (CYN) in water supply reservoirs. CYN is a powerful hepatotoxic alkaloid implicated in outbreaks of human sicknesses. We detected CYN in different sources of water in Northeastern Brazil using molecular and immunological techniques. The highest concentrations of toxin occurred in the Jucazinho reservoir with the phytoplankton containing the potentially CYN-producing C. raciborskii and Sphaerospermopsis aphanizomenoides (previously known as Aphanizomenon aphanizomenoides). The polyketide synthase (PKS) and peptide synthetase (PS), which are directly related to the ability to produce CYN, were found in all the analyzed samples. The result of the present study emphasizes the need to improve monitoring of CYN in water bodies used for drinking and recreation, in order to avoid exposure of human populations to this toxin.