Yamamoto, Y., Yasuda, M., Mori, E. and Maeda, K. (1999) Failure to Confirm a Synergistic Effect between the K-Variant of the Butyrylcholinesterase Gene and the Epsilon4 Allele of the Apolipoprotein Gene in Japanese Patients with Alzheimer’s Disease. Journal of Neurology, Neurosurgery & Psychiatry, 67, 94-96. http://dx.doi.org/10.1136/jnnp.67.1.94

has been cited by the following article:

• TITLE: Prevalence of Wild-Type Butyrylcholinesterase Genotype in Patients with Alzheimer’s Dementia

  AUTHORS: Beate Mueller, Georg Adler

  KEYWORDS: Butyrylcholinesterase, Alzheimer’s Disease, Genotype

  JOURNAL NAME: World Journal of Neuroscience, Vol.5 No.3, June 2, 2015

  ABSTRACT: Approximately, two-thirds patients with Alzheimer’s disease (AD) are reported to have homozygous wild-type butyrylcholinesterase (BuChE) gene expression. It is associated with a higher rate of hydrolysis of acetylcholine, which ultimately leads to increase in the levels of BuChE in advanced stages of the disease. Rivastigmine, a dual inhibitor of acetylcholinesterase (AChE) and BuChE, might be of additional benefit in patients with AD with wild-type BuChE allele.