Zhang, J., Hu, X., Gao, W., Qu, Z., Guo, H., Liu, Z. and Liu, C. (2014) Pharmacokinetic Study on Costunolide and Dehydrocostuslactone after Oral Administration of Traditional Medicine Aucklandia Lappa Decne by LC/MS/MS. Journal of Ethnopharmacology, 151, 191-197.
http://dx.doi.org/10.1016/j.jep.2013.10.024

has been cited by the following article:

• TITLE: Chemical Composition, Antibacterial Activity of the Essential Oil from Roots of Radix aucklandiae against Selected Food-Borne Pathogens

  AUTHORS: Jinxiu Liu, Defeng Huang, Donglin Hao, Qingping Hu

  KEYWORDS: Radix aucklandiae, Essential Oil, GC-MS, Antibacterial Activity

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.5 No.13, November 25, 2014

  ABSTRACT: Radix aucklandiae from Yunnan Province in China is a significant medicinal plant. In the present study, the essential oil composition fromRadix aucklandiae roots was investigated by gas chromatography-mass spectrometry (GC-MS). A total of 23 compounds representing 57.95% of the essential oil were tentatively identified. The main constituents were eremanthin (12.74%), d-Guaiene (6.26%), ζ-Himachalene (6.16%) and l-Caryophyllene (4.84%). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the essential oil from R. aucklandiae were evaluated against three Gram-positive bacteria (Staphylococcus aureus, Staphylococcus albus and Bacillus subtilis) three Gram-negative bacteria (Salmonella typhimurium, Escherichia coli and Shigella dysenteriae). Results revealed that the essential oil exhibited significant in vitro antimicrobial property. Among all the tested microorganisms, the essential oil showed the strongest inhibitory effect against S. typhimurium. The data of this study suggests that the essential oil from Radix aucklandiae has great potential for application as a natural antimicrobial agent to preserve food.