TITLE:
The Use of Left Ventricular Myocardial Stiffness Index as a Predictor of Myocardial Performance in Patients with Systemic Hypertension
AUTHORS:
Muataz F. Hussein, Asia H. Al-Mashhadani, Samar I. Essa
KEYWORDS:
Left Ventricular Stiffness, Systemic Hypertension
JOURNAL NAME:
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology,
Vol.3 No.3,
August
13,
2014
ABSTRACT:
Our
aim was to investigate the changes in the myocardium stiffness index for
patients suffering from systemic hypertension, and to assess their left
ventricular performance. We studied 263 hypertensive patients and 166 healthy
subjects as a control group. By using conventional Doppler echocardiography, the following parameters were measured—Left ventricular end diastolic diameter, left ventricular
end systolic diameter, transmitral early velocity, isovolumic relaxation time,
and isovolumic contraction time. Tissue Doppler imaging (TDI) was used in the
measurements of the
early mitral annular velocity (Ea) and the diastolic stiffness was obtained by
calculating the
ratio E\Ea\LVIDd. Index myocardial performance (IMP) was calculated according
to following
equation (IVCT + IVRT)/ET for both the control group and hypertensive group.
Results reveal that
the differences in the
average value of transmitral early filling velocity (E) between patients and control groups for age range (20 - 49) and (50 - 80) were (.91%)
and (.69%) respectively with p value >0.05 for both
groups, and the changes in LVIDd
between patients and control groups
were 0.42% and 1.29% for age
ranges (20 - 49) and (50 - 80) respectively with p value >0.05 for
both age groups. A significant difference in IMP between patients and controls
has also been
observed and the changes were 29.54% and
30.43% for age range (20 - 49) and (50 - 80) respectively with p value 0.05) for
both age groups. In
conclusion, LV myocardial diastolic stiffness index and IMP are increased in
hypertensive patients.