TITLE:
Solitary Plasmacytoma of the Zygoma in a 70-Year-Old Nigerian: A Case Report and Review of Literature
AUTHORS:
Obitade S. Obimakinde, Olufemi J. Taiwo, Ahmed O. Lawal, Akinyele O. Adisa, Victoria N. Okoje, Juwon T. Arotiba
KEYWORDS:
Solitary Plasmacytoma, Myeloma, Zygoma
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.3 No.4,
July
11,
2014
ABSTRACT:
Purpose: Solitary
bone plasmacytoma [SBP] is a localised variant of plasma cell tumor which
commonly affects the axial skeleton but rarely found in the maxillofacial
region. We hereby report an unusual case of solitary plasmacytoma of the right
zygomatic bone in a 70-year-old Nigerian. Case Report: The patient presented
with a painless right zygomatic swelling of 2 years duration. Examination
showed that the swelling was of mixed consistency [mostly bony but firm in some
areas] and it measured about 8 × 8 cm. Radiographic
examination revealed an osteolytic lesion over the right zygoma with
involvement of the apex and lateral wall of the antrum. An initial working diagnosis of ossifying fibroma was made
and the patient was scheduled for surgery. Histological staining with H & E
and immunohistochemistry of the surgical specimen however confirmed a diagnosis
of SBP. Serum monoclonal protein and Bence Jones proteinuria was negative
throughout the follow up period. Conclusion: SBP of the maxillofacial region is
amenable to surgery combined with postoperative radiotherapy. However,
prognosis can be worsened with tumor recurrence or dissemination into MM. Thus
patients with SBP must be closely followed up after treatment so that immediate
therapeutic steps can be taken if recurrence or systemic dissemination is
encountered.