TITLE:
A Modified Method for the Synthesis of Tetradentate Ligand Involving Peptide Bond
AUTHORS:
Pulimamidi Rabindra Reddy, Ravula Chandrashekar, Hussain Shaik, Battu Satyanarayana
KEYWORDS:
Amide Bond Formation, Tetradentate Ligand, Peptide Bond, Coupling Reagent
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.4 No.2,
May
26,
2014
ABSTRACT: In view of the importance of picolinic acid (Pa) in preventing cell growth and arresting cell cycle, attempts were made to design, synthesize and characterize two new Pa based tetradentate ligands (DPPTR and DPPTY) with a modified procedure. The procedure reported here avoids by-products and provides better yield and purity.