Article citationsMore>>
Dvorak, A.M., Onderdonk, A.B., McLeod, R.S., Monahan-Earley, R.A., Cullen, J., Antonioli, D.A., Blair, J.E., Morgan, E.S., Cisneros, R.L., Estrellla, P., Cohen, Z. and Silen, W. (1993) Axonal Necrosis of Enteric Automatic Nerves in Continent Heal Pouches Implications for Pathogenesis of Crohn’s Disease. Annals of Surgery, 217, 260-271.
http://dx.doi.org/10.1097/00000658-199303000-00008
has been cited by the following article:
-
TITLE:
Anti-Colorectal Cancer Chemotherapy-Induced Diarrhoea: Current Treatments and Side-Effects
AUTHORS:
Rachel M. McQuade, Joel C. Bornstein, Kulmira Nurgali
KEYWORDS:
Oxaliplatin; Irinotecan, 5-Fluorouracil, Cisplatin, Carboplatin, Chemotherapy, Colorectal Cancer, Chemotherapy-Induced Diarrhoea
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.5 No.7,
April
14,
2014
ABSTRACT:
Chemotherapy-induced
diarrhoea (CID) is a common side-effect experienced by patients being treated
with a variety of antineoplastic agents. Approximately 80% of patients undergoing
chemotherapeutic treatment for colorectal and other gastrointestinal cancers
present with CID; moreover, about 5% of early deaths associated with
combination anti-cancer chemotherapy are due to CID. Chronic post-treatment
diarrhoea amongst cancer survivors can persist for more than 10 years greatly
effecting long-term quality of life. Gastrointestinal toxicities such as
diarrhoea and vomiting are amongst the primary contributors to dose reductions
and delays throughout anti-cancer treatment, presenting a significant hurdle in
clinical management of anti-cancer regimes and often result in sub-optimum
treatment. However, little is known about pathophysiological mechanisms
underlying CID. This work provides a review of chemotherapy-induced diarrhoea,
current management guidelines, and shortcomings of current treatments as well
as emerging and already existing anti-diarrhoeal treatments potentially
suitable for CID.
Related Articles:
-
Iliass Charif, Mohamed El Abkari, Adil Ibrahimi, Mounia El Yousfi, Mounia El Yousfi
-
Robert Jansen, Stanley Zaslau
-
John Chia, Andrew Chia, David Wang, Rabiha El-Habbal, Sitaraman Jyotheeswaran, Eric McCloud
-
Mohamed Alhaj Moustafa
-
Makiko Asakura, Kazuko Sakimoto, Hiroyuki Miura