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Kowalski, H.J. and Abelmann, W.H. (1953) The Cardiac Output at Rest in Laennec’s Cirrhosis. Journal of Clinical Investigation, 32, 1025-1033. http://dx.doi.org/10.1172/JCI102813

has been cited by the following article:

  • TITLE: Prolonged QTc Interval Is an Electrophysiological Hallmark of Cirrhotic Cardiomyopathy

    AUTHORS: Adnan Bashir Bhatti, Farhan Ali, Siddique Akbar Satti

    KEYWORDS: Cirrhosis; QT Interval; Cirrhotic Cardiomyopathy

    JOURNAL NAME: Open Journal of Internal Medicine, Vol.4 No.1, March 26, 2014

    ABSTRACT: BACKGROUND: Cirrhotic Cardiomyopathy is a relatively ill-characterized condition, which is often under-diagnosed due to absence of defined diagnostic criteria. ECG showing corrected QT Interval prolongation is the most suitable available option for diagnosis of this condition. OBJECTIVE: To determine the frequency of corrected QT interval prolongation in patients with liver cirrhosis. METHODOLOGY: Patients (n = 166) with confirmed cirrhosis, 30 years or older, presented in the outpatient and emergency department of medicine at Capital Hospital Islamabad between 1 October 2011 and 30 September 2012, were enrolled in this cross-sectional study after taking consent. ECG was done using calibrated ECG machine, and the QT Interval was measured. Corrected QT was calculated using Bazett’s formula and a QTc of more than 0.44 seconds was considered as being prolonged. RESULTS: The mean age of the patients was 57.05 ± 12.03 years. The corrected QT Interval varied from 337 ms to 560 ms. The mean QTc Interval was 429.92 ms ± 45.11. QTc was prolonged in 41 out of 166 patients (24.7%). Frequency of QTc prolongation was 4.5% in Child Pugh Grade A, 23.2% in Child Pugh Grade B, and 32.0% in Child Pugh Grade C. Association of Child Pugh Scoring with QTc prolongation was determined and found to be statistically significant (P