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http://dx.doi.org/10.3987/COM-94-S(B)35

has been cited by the following article:

• TITLE: Synthesis, Resolution and Absolute Configuration of 2,3-Dihydro-2-Tert-Butyl-3-N-Benzylquinazolin-4-One: A Possible Chiral Auxiliary for Synthesis of β-Amino Cyclohexancarboxylic Acid

  AUTHORS: Fanny A. Cabrera-Rivera, Jaime Escalante

  KEYWORDS: Chiral Auxiliary; 2-Tert-Butyl-Quinazolin-4-One

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.4 No.1, March 17, 2014

  ABSTRACT: 3-Benzyl-2-(tert-butyl)-2,3-dihydroquinazolin-4(1H)-one rac-11 was resolved via the preparation of diastereomers with N-phthalyl-L-alanine chloride and its absolute configuration was determined by X-ray crystallographic analysis. This heterocycle has potential as a substrate chiral in asymmetric induction due to the steric effects of its tert-butyl group.