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http://dx.doi.org/10.1007/BF01622200

has been cited by the following article:

• TITLE: Is osteoporosis risk in anorexia nervosa underestimated? A case report series

  AUTHORS: Bruno Pacciardi, Claudio Cargioli, Simone Belli, Biagio Cotugno, Samanta Augusto, Luca Di Paolo, Mauro Mauri

  KEYWORDS: Anorexia Nervosa; Amenorrhea; Osteoporosis; Fracturerisk; DXA; BMD

  JOURNAL NAME: Open Journal of Internal Medicine, Vol.3 No.4, December 11, 2013

  ABSTRACT: Introduction: Anorexia nervosa (AN) is a mental disorder whose features are deliberate weight loss, disordered body image, and intrusive overvalued fears of gaining weight. Long-term consequences of AN include endocrine dysfunctions leading to secondary amenorrhea, bone loss and/or osteoporosis with an increased risk of bone fracture. Therefore young women with AN may develop a risk for bone fractures comparable to that of postmenopausal women. Methods: In this case report series Bone Mineral Density (BMD) was examined by Dual energy X-ray Absorptiometry (DXA) in 19 hospitalized patients with diagnosis of AN and prolonged amenorrhea. Results: All patients showed a lumbar/femoral bone loss or osteoporosis, with an increased fracture risk comparable to that of postmenopausal women. Conclusions: Our observation suggests that DXA evaluation of anorexic patients with prolonged amenorrhea would be helpful to prevent fracture risk in this population of patients. However, although DXA is almost routinely recommended in women over 65, it is not in young AN patients with prolonged amenorrhea.