TITLE:
A Fluorescence Ratiometric Probe for Detection of Cyanide in Water Sample and Living Cells
AUTHORS:
Lingliang Long, Lin Wang, Yanjun Wu
KEYWORDS:
Organic Fluorescence Materials; Fluorescent Probes; Cyanide; Fluorescence Imaging
JOURNAL NAME:
Advances in Materials Physics and Chemistry,
Vol.3 No.8,
December
6,
2013
ABSTRACT:
In the present work, Compound 1 has been synthesized as a novel fluorescence
ratiometric probe for CN-. Upon treatment with CN-, Probe 1 exhibited a fluorescence
ratiometric response, with the emission wavelength shift from 570 nm to 608 nm.
When 90 μM CN-was introduced, the emission ratios (I570/I608)
of the probe changed dramatically
from 0.52156 to 4.21472. The detection limit was also measured to be 0.24 μM (S/N = 3). In addition, Probe 1 had a selective response to CN-, while other anions caused
nearly no interference. The sensing reaction product of Probe 1 with CN-was characterized
by 1H NMR spectra and ESI Mass spectrometry. Furthermore, Probe 1 has been successfully applied to
detect CN-in natural water samples. The fluorescence imaging
experiments in living cells also demonstrated that Probe 1 could monitor CN-in biological samples.