TITLE:
Prevalence and predictors of urinary tract infections among children with cerebral palsy in Makurdi, Nigeria
AUTHORS:
Emmanuel Adémólá Anígilájé, Terkaa Terrumun Bitto
KEYWORDS:
Urinary Tract Infection; Cerebral Palsy Children; Prevalence; Predictors
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.3 No.4,
November
28,
2013
ABSTRACT:
Background: Children with cerebral palsy (CP) are
prone to urinary tract infection (UTI), a common cause of childhood morbidity
and mortality. However, there has been no report regarding the prevalence of
UTI among this group of children inNigeria. Objectives: The study aims
at determining the prevalence and the possible predictors of UTI in children
with CP compared to age and sex matched children without CP. Methods: A
prospective cross-sectional study was carried out among consecutive children
with CP at the Neurologic Clinic in the Paediatric Department of the Federal
Medical Centre, Makurdi, Nigeria, from December 2011 to May 2013. Results: The
age range of the studied population was between 2 and 15 years with a mean age
of 8.63 ± 3.83 years including 30 males and 22 females. UTI was confirmed in 20
(38.5%) children with cerebral palsy compared to 2 children (3.8%) without CP
(p value 0.000). Among children with CP, Escherichia
coli was the commonest organism isolated in 9 (9/20, 45.0%), Streptococcus faecalis in 4 (20.0%), Staphylococcus aureus in 3 (15%), while
both Proteus spp., and Klebsiella spp., were isolated in 2
children (10.0%) each. Escherichia coli was also found in the 2 children without CP. All the organisms were resistant
to co-trimoxazole, nalidixic acid, nitrofuratoin and amoxiclav, while they were
100% sensitive to ceftriazone and the quinolones. In a univariate regression,
analysis only moderate to severe gross motor dysfunction predicted the risk of
UTI (OR = 54.81, 95%CI, 2.27 - 1324.00, p value 0.014). Conclusion: Efforts
should be put in place to aid mobility among children with CP in order to
reduce risk of UT.