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has been cited by the following article:

• TITLE: The angiotension converting enzyme (ACE) gene I/D polymorphism in different ethnic groups of geriatric age living in the Far North

  AUTHORS: Natalya Arkhipova, Elena Popova, Lena Grigorieva

  KEYWORDS: CHD; Geriatric Age; Risk Factors; ACE Gene; Non-Indigenous and Yakut Patients

  JOURNAL NAME: Health, Vol.6 No.5, February 24, 2014

  ABSTRACT: The study of ACE gene I/D polymorphism has been carried out in elderly, senile and long-liver patients with coronary heart disease (CHD) taking into account their nationality, age and sex. It has been recorded that with the increase of age there is a decrease in the frequency of the genotype ACE*I/*I and a tendency of increase in the frequency of the genotype ACE*D/*D. A comparative analysis of genotypes АСЕ*D/*D and АСЕ*D/*I has showed sex differences in the frequency of homozygous genotype detection. Left ventricular hypertrophy can be observed significantly more often among carriers of genotype ACE*I/*I established by Sokolow-Lyon ECG signs. Association analysis of ACE gene I/D polymorphism has registered significant differences in BMI and blood lipid parameters.