(Z)-N-(3-(2-Chloro-4-nitrophenyl)-4-methylthiazol-2(3H)-ylidene) Pivalamide: Synthesis and Crystal Structure
Aamer Saeed, Michael Bolte
DOI: 10.4236/jcpt.2011.13007   PDF    HTML     4,576 Downloads   9,457 Views   Citations


Synthesis of the title compound was carried out by base-catalyzed cyclization of 1-pivaloyl-3-(2-chloro-4-nitrophenyl) thiourea with α-bromoacetone produced in situ. The structure was confirmed by the spectroscopic and elemental analysis and single crystal X-ray diffraction data. It crystallizes in the triclinic space group P-1 with unit cell dime sions a = 8.7137(10), b = 10.2010(14), c = 10.6593(13), α = 62.671(9), β = 82.701(10), γ = 79.762(10), V = 827.21(8) ų, Z = 2.

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A. Saeed and M. Bolte, "(Z)-N-(3-(2-Chloro-4-nitrophenyl)-4-methylthiazol-2(3H)-ylidene) Pivalamide: Synthesis and Crystal Structure," Journal of Crystallization Process and Technology, Vol. 1 No. 3, 2011, pp. 41-48. doi: 10.4236/jcpt.2011.13007.

Conflicts of Interest

The authors declare no conflicts of interest.


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