In Vitro Evaluation of Polyurethane-Chitosan Scaffolds for Tissue Engineering


In this work the use of Polyurethane (PU)-Chitosan(CH) scaffolds prepared by thermal induced phase separation (TIPS) for osteoblast proliferation and bone mineralization is described. Primary rat calvaria osteoblasts were seeded in the scaffolds and it was shown that supported cell adhesion and growth. The behavior osteoblast cells growing in the scaffold in function of the different ratio of PU and CH is presented. The results showed that TIPS is an appropriate technique for the production of PU-CH scaffolds with high potential for application as cell scaffolds in bone tissue engineering.

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I. Olivas-Armendariz, P. García-Casillas, A. Estrada, A. Martínez-Villafañe, L. Rosa and C. Martínez-Pérez, "In Vitro Evaluation of Polyurethane-Chitosan Scaffolds for Tissue Engineering," Journal of Biomaterials and Nanobiotechnology, Vol. 3 No. 4, 2012, pp. 440-445. doi: 10.4236/jbnb.2012.34044.

Conflicts of Interest

The authors declare no conflicts of interest.


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