Long term clinical and dermoscopic follow-up of a child with a Spitz nevus


Background: Spitz nevus is uncommon, benign melanocytic neoplasm that may show some clinical, dermoscopical and histological features of melanoma. It occurs often in childhood, but may appear also in early adulthood. Rare congenital cases have been reported in literature. It is frequently located on the face and the lower extremities, but in some cases may appears on the trunk. Methods: We report a case of a 9-years-old girl presented to our Dermatology Unit because of the presence of a pigmented lesion on her right leg, 4 mm in diameter, which was clinically and dermoscopically diagnosed as Spitz nevus. We described the clinical and dermoscopic features that we observed every six months, over 11 years follow-up period. Objective: Our observation show that the globular, the starburst, the homogeneous patterns and diffuse brown colour with diffuse hypopigmented areas may be the different expression that correspond to possible evolutionary phases of pigmented Spitz nevus.

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Scalvenzi, M. , Grazia Francia, M. , Palmisano, F. and Costa, C. (2012) Long term clinical and dermoscopic follow-up of a child with a Spitz nevus. Open Journal of Pediatrics, 2, 253-256. doi: 10.4236/ojped.2012.23040.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Pizzichetta, M.A., Argenziano, G., Grandi, G., et al. (2002) Morphologic changes of a pigmented Spitz nevus assessed by dermoscopy. Journal of the American Aca- demy of Dermatology, 47, 137-139. doi:10.1067/mjd.2002.122193
[2] Argenziano, G., Scalvenzi, M., Staibano, S., et al. (1999) Dermatoscopic pitfalls in differentiating pigmented Spitz naevi from cutaneous melanomas. British Journal of Dermatology, 141, 788-793. doi:10.1046/j.1365-2133.1999.03150.x
[3] Ferrara, G., Argenziano, G., Soyer, H.P., et al. (2005) The spectrum of Spitz nevi: A clinicopathologic study of 83 cases. Archives of Dermatology, 141, 1381-1387. doi:10.1001/archderm.141.11.1381
[4] Gill, M., Cohen, J., Renwick, N., et al. (2004) Genetic similarities between Spitz nevus and Spitzoid melanoma in children. Cancer, 101, 2636-2640. doi:10.1002/cncr.20680
[5] Yan, A.C. and Smolinski, K.N. (2005) Melanocytic nevi: Challenging clinical situations in pediatric dermatology. Advances in Dermatology, 21, 65-80. doi:10.1016/j.yadr.2005.05.001
[6] Brunetti, B., Nino, M., Sammarco, E., et al. (2005) Spitz naevus: A proposal for management. Journal of the European Academy of Dermatology and Venereology, 19, 391-393. doi:10.1111/j.1468-3083.2004.01137.x
[7] Argenziano, G., Zalaudek, I., Ferrara, G., et al. (2007) Involution: The natural evolution of pigmented Spitz and Reed nevi? Archives of Dermatology, 143, 549-551.
[8] Nino, M., Brunetti, B., Delfino, S., et al. (2009) Spitz nevus: Follow-up study of 8 cases of childhood starburst type and proposal for management. Dermatology, 218, 48-51.
[9] Piccolo, D., Ferrari, A. and Peris, K. (2003) Sequential dermoscopic evolution of pigmented Spitz nevus in childhood. Journal of the American Academy of Dermatology, 49, 556-558.

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