Dual-Energy Subtraction X-Ray Digital Tomosynthesis: Basic Physical Evaluation


The present study was performed to determine the potential of applying dual-energy subtraction (DES) digital tomo-synthesis to basic physical evaluations. Volumetric X-ray DES digital tomosysnthesis was used to obtain an image of a detectability phantom (an artificial lesion). The image quality of DES digital tomosynthesis was compared to that of DES radiography. The purpose of this study was to determine enhanced visibility quantified in terms of the contrast- to-noise ratio, figure-of-merit, and root-mean-square error. In the in-focus plane, the image quality is better by DES digital tomosynthesis than by DES radiography. The potential usefulness of DES digital tomosynthesis for evaluating a detectability phantom was demonstrated. Further studies are required to determine the ability of DES digital tomosyn-thesis to quantify the spatial relationships between the artificial lesion components of these devices, as well as to iden- tify lesions with diagnostic consequences.

Share and Cite:

T. Gomi and M. Nakajima, "Dual-Energy Subtraction X-Ray Digital Tomosynthesis: Basic Physical Evaluation," Open Journal of Medical Imaging, Vol. 2 No. 3, 2012, pp. 111-117. doi: 10.4236/ojmi.2012.23021.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] W. R. Brody, G. Butt, A. Hall and A.Macovski, “A Me- thod for Selective Tissue and Bone Visualization Using Dual-Energy Scanned Projection Radiography,” Medical Physics, Vol. 8, No. 3, 1981, pp. 353-357. doi:10.1118/1.594957
[2] L. A. Lehmann, R. E. Alvarez, A. Macovski, W. R. Brody, N. J. Pelc, S. J. Riederer and A. L. Hall, “Generalized Image Combinations in Dual KVP Digital Radiography,” Medical Physics, Vol. 8, No. 5, 1981, pp. 659-667. doi:10.1118/1.595025
[3] R. A. Kruger, J. D. Armstrong, J. A. Sorenson and L. T. Niklason, “Dual Energy Film Subtraction Technique for Detecting Calcification in Solitary Pulmonary Nodules,” Radiology, Vol. 140, No. 1, 1981, pp. 213-219.
[4] J. M. Sabol, G. B. Avinash, F. Nicolas, B. Claus, Z. Jian- guo and J. T. Dobbins, “The Development and Charac- terization of a Dual-Energy Subtraction Imaging System for Chest Radiography Based On CsI:Tl Amorphous Silicon Flat-Panel Technology,” Proceedings of SPIE on Physics of Medical Imaging, Vol. 4320, 2001, pp. 399- 408. doi:10.1117/12.430897
[5] R. G. Fraser, N. M. Hickey, L. T. Niklason, E. A. Sabbagh, R. F. Luna, C. B. Alexander, C. A. Robinson, A. L. Kat- zenstein and G. T. Barnes, “Caccification in Pulmonary Nodules: Detection with Dual-Energy Digital Radiography,” Radiology, Vol.160, No. 3, 1986, pp. 595-601.
[6] L. T. Niklason, N. M. Hickey, D. P. Chakraborty, E. A. Sabbagh, M. V. Yester, R. G. Fraser and G. T. Brans, “Si- mulated Pulmonary Nodules: Detection with Dual-Energy versus Conventional Radiography,” Radiology, Vol. 160, No. 3, 1986, pp. 589-593.
[7] R. A. Kuger, “Dual-Energy Electric Sanning-Slit Fluoro- graphy for the Determination of Vertebral Bone Mineral Content,” Medical Physics, Vol. 14, No. 4, 1987, pp. 562- 566. doi:10.1118/1.596068
[8] S. Molloi, A. Ersahin, J. Tang, J. Hicks and C. Y. Leung, “Quantification of Volumetric Coronary Blood Flow with Dual-Energy Digital Subtraction Angiography,” Circula- tion, Vol. 93, No. 10, 1996, pp. 1919-1927. doi:10.1161/01.CIR.93.10.1919
[9] J. T. Dobbins and D. J. Godfrey, “Digital X-Ray Tomo- synthesis: Current State of the Art and Clinical Potential,” Physics in Medicine and Biology, Vol. 48, No. 19, 2003, pp. R65-R106. doi:10.1088/0031-9155/48/19/R01
[10] A.-K. Carton, S. C. Gavenonis, J. A. Currivan, E. F. Co- nant, M. D. Schnall and A. D. A. Maidment, “Dual-En- ergy Contrast-Enhanced Digital Breast Tomosynthesis: A Feasibility Study,” British Journal of Radiology, Vol. 83, No. 988, 2009, pp. 344-350. doi:10.1259/bjr/80279516
[11] E. Samei and R. S. Saunders Jr., “Dual-Energy Contrast- Enhanced Breast Tomosynthesis: Optimization of Beam Quality for Dose and Image Quality,” Physics in Medi- cine and Biology, Vol. 56, No. 19, 2011, pp. 6359-6378. doi:10.1088/0031-9155/56/19/013
[12] T. Gomi, M. Nakajima, H. Fujiwara and T. Umeda, “Com- parison of Chest Dual-Energy Subtraction Digital Tomosynthesis Imaging and Dual-Energy Subtraction Radiog- raphy to Detect Simulated Pulmonary Nodules with and without Calcifications: A Phantom Study,” Academic Ra- diology, Vol. 18, No. 2, 2011, pp. 191-196. doi:10.1016/j.acra.2010.09.021
[13] S. Sone, T. Kasuga, F. Sakai, J. Aoki, I. Izuno, Y. Tanizaki, H. Shigeta and K. Shibata, “Development of a High- Resolution Digital Tomosynthesis System and Its Clinical Application,” Radiographics, Vol. 11, No. 5, 1991, pp. 807-822.
[14] T. Gomi and H. Hirano, “Clinical Potential of Digital Linear Tomosynthesis Imaging of Total Joint Arthroplasty,” Journal of Digital Imaging, Vol. 21, No. 3, 2008, pp. 312-322. doi:10.1007/s10278-007-9040-9
[15] L. D. Justin, X. Tong and M. Sabee, “Dual-Energy Car- diac Imaging: An Image Quality and Dose Comparison for flat-Panel Detector and X-Ray Image Intensifier,” Phy- sics in Medicine and Biology, Vol. 52, No. 1, 2007, pp. 183-186. doi:10.1088/0031-9155/52/1/012
[16] N. M. Hickey, L. T. Niklason, E. Sabbagh, R. G. Fraser and G. T. Barnes, “Dual-Energy Digital Radiographic Quantification of Calcium in Simulated Pulmonary Nod- ules,” American Journal of Roentgenology, Vol. 148, No. 1, 1987, pp. 19-24.
[17] T. Ishigaki, S. Sakuma, Y. Horikawa, M. Ikeda and H. Ya- maguchi, “One-Shot Dual-Energy Subtraction Imaging,” Radiology, Vol. 161, No. 1, 1986, pp. 271-273.
[18] T. Ishigaki, S. Sakuma and M. Ikeda, “One-Shot Dual- Energy Subtraction Chest Imaging with Computed Radi- ography: Clinical Evaluation of Film Images,” Radiology, Vol. 168, No. 1, 1988, pp. 67-72.
[19] H. Nishitani, Y. Umezu, K. Ogawa, H. Yuzurihara, H. Tanaka and K. Matsuura, “Dual-Energy Projection Radi- ography Using Condenser X-Ray Generator and Digital Radiography Apparatus,” Radiology, Vol. 161, No. 2, 1986, pp. 533-535.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.