[1]
|
Li, X., Tang, Z., Wen, L., et al. (2021) Matrine: A Review of Its Pharmacology, Pharmacokinetics, Toxicity, Clinical Application and Preparation Researches. Journal of Ethnopharmacology, 269, Article ID: 113682. https://doi.org/10.1016/j.jep.2020.113682
|
[2]
|
Yang, Y., Zhang, Z., Li, S., et al. (2014) Synergy Effects of Herb Extracts: Pharmacokinetics and Pharmacodynamic Basis. Fitoterapia, 92, 133-147. https://doi.org/10.1016/j.fitote.2013.10.010
|
[3]
|
Shao, J., Wang, T., Yan, Y., et al. (2014) Matrine Reduces Yeast-to-Hypha Transition and Resistance of a Fluconazole-Resistant Strain of Candida albicans. Journal of Applied Microbiology, 117, 618-626. https://doi.org/10.1111/jam.12555
|
[4]
|
Jia, F., Zhou, Q., Li, X., et al. (2019) Total Alkaloids of Sophora alopecuroides and Matrine Inhibit Auto-Inducer 2 in the Biofilms of Staphylococcus epidermidis. Microbial Pathogenesis, 136, Article ID: 103698. https://doi.org/10.1016/j.micpath.2019.103698
|
[5]
|
Zhang, B., Liu, Z., Li, Y., et al. (2011) Antiinflammatory Effects of Matrine in LPS-Induced Acute Lung Injury in Mice. European Journal of Pharmaceutical Sciences, 44, 573-579. https://doi.org/10.1016/j.ejps.2011.09.020
|
[6]
|
Jiang, K., Guo, S., Yang, J., et al. (2019) Matrine Alleviates Staphylococcus aureus Lipoteichoic Acid-Induced Endometritis via Suppression of TLR2-Mediated NF-kappa B Activation. International Immunopharmacology, 70, 201-207. https://doi.org/10.1016/j.intimp.2019.02.033
|
[7]
|
Dai, G., Li, B., Xu, Y., et al. (2021) Synergistic Interaction between Matrine and Paracetamol in the Acetic Acid Writhing Test in Mice. European Journal of Pharmacology, 895, Article ID: 173869. https://doi.org/10.1016/j.ejphar.2021.173869
|
[8]
|
Zhang, X., Jin, L., Cui, Z., et al. (2016) Antiparasitic Effects of Oxymatrine and Matrine against Toxoplasma gondii in Vitro and in Vivo. Experimental Parasitology, 165, 95-102. https://doi.org/10.1016/j.exppara.2016.03.020
|
[9]
|
Chang, C., Liu, S.P., Fang, C.H., et al. (2013) Effects of Matrine on the Proliferation of HT29 Human Colon Cancer Cells and Its Antitumor Mechanism. Oncology Letters, 6, 699-704. https://doi.org/10.3892/ol.2013.1449
|
[10]
|
Wang, L., Lu, J., Sun, W., et al. (2017) Hepatotoxicity Induced by Radix Sophorae tonkinensis in Mice and Increased Serum Cholinesterase as a Potential Supplemental Biomarker for Liver Injury. Experimental and Toxicologic Pathology, 69, 193-202. https://doi.org/10.1016/j.etp.2017.01.003
|
[11]
|
Grove, J. and Marsh, M. (2011) The Cell Biology of Receptor-Mediated Virus Entry. Journal of Cell Biology, 195, 1071-1082. https://doi.org/10.1083/jcb.201108131
|
[12]
|
Lednicky, J.A., Tagliamonte, M.S., White, S.K., et al. (2021) Independent Infections of Porcine Deltacoronavirus among Haitian Children. Nature, 600, 133-137. https://doi.org/10.1038/s41586-021-04111-z
|
[13]
|
Garcia-Sastre, A. (2017) Ten Strategies of Interferon Evasion by Viruses. Cell Host & Microbe, 22, 176-184. https://doi.org/10.1016/j.chom.2017.07.012
|
[14]
|
Qin, F., Liu, Y., Xia, W.L., et al. (2020) Study on the in Vitro Anti-Porcine Reproductive and Respiratory Syndrome Virus Effect of Three Extracts of Lobelia chinensis Lour. Journal of Henan Agricultural University, 54, 462-470.
|
[15]
|
Zhao, X., Sun, N. and Bai, X.Y. (2013) Inhibitory Action and Mechanism of Matrine against Porcine Reproductive and Respiratory Syndrome Virus in Vitro. Chinese Journal of Veterinary Science, 33, 808-812.
|
[16]
|
Sun, N., Wang, Z.W., Wu, C.H., et al. (2014) Antiviral Activity and Underlying Molecular Mechanisms of Matrine against Porcine Reproductive and Respiratory Syndrome Virus in Vitro. Research in Veterinary Science, 96, 323-327. https://doi.org/10.1016/j.rvsc.2013.12.009
|
[17]
|
Sun, N., Yu, T., Zhao, J., et al. (2015) Antiviral Activities of Natural Compounds Derived from Traditional Chinese Medicines against Porcine Circovirus Type 2 (PCV2). Biotechnology and Bioprocess Engineering, 20, 180-187. https://doi.org/10.1007/s12257-014-0520-8
|
[18]
|
Wei, L., Zhu, Z., Wang, J., et al. (2009) JNK and p38 Mitogen-Activated Protein Kinase Pathways Contribute to Porcine Circovirus Type 2 Infection. Journal of Virology, 83, 6039-6047. https://doi.org/10.1128/JVI.00135-09
|
[19]
|
Xu, Y., Sun, P., Wan, S., et al. (2020) The Combined Usage of Matrine and Osthole Inhibited Endoplasmic Reticulum Apoptosis Induced by PCV2. BMC Microbiology, 20, Article No. 303. https://doi.org/10.1186/s12866-020-01986-2
|
[20]
|
Cheung, A.K. (2003) Transcriptional Analysis of Porcine Circovirus Type 2. Virology, 305, 168-180. https://doi.org/10.1006/viro.2002.1733
|
[21]
|
Sun, N., Sun, P., Lv, H., et al. (2016) Matrine Displayed Antiviral Activity in Porcine Alveolar Macrophages Co-Infected by Porcine Reproductive and Respiratory Syndrome Virus and Porcine Circovirus Type 2. Scientific Reports, 6, Article No. 24401. https://doi.org/10.1038/srep24401
|
[22]
|
Zhang, Y., Zhang, X., Chen, N., et al. (2017) Four Matrine-Based Alkaloids with Antiviral Activities against HBV from the Seeds of Sophora alopecuroides. Organic Letters, 19, 424-427. https://doi.org/10.1021/acs.orglett.6b03685
|
[23]
|
Zhang, Y., Luo, D., Yang, L., et al. (2018) Matrine-Type Alkaloids from the Roots of Sophora flavescens and Their Antiviral Activities against the Hepatitis B Virus. Journal of Natural Products, 81, 2259-2265. https://doi.org/10.1021/acs.jnatprod.8b00576
|
[24]
|
Chen, J., Shen, H., Niu, M., et al. (2016) Anti-Hepatitis B Virus Effect of Matrine-Type Alkaloid and Involvement of p38 Mitogen-Activated Protein Kinase and Tumor Necrosis Factor Receptor-Associated Factor. Virus Research, 215, 104-113. https://doi.org/10.1016/j.virusres.2015.12.005
|
[25]
|
Li, Y.H., Wu, Z.Y., Tang, S., et al. (2017) Evolution of Matrinic Ethanol Derivatives as Anti-HCV Agents from Matrine Skeleton. Bioorganic & Medicinal Chemistry Letters, 27, 1962-1966. https://doi.org/10.1016/j.bmcl.2017.03.025
|
[26]
|
Huang, J., Xiang, S.Y., Lv, M., et al. (2018) 14-Formyl-15-aryloxy/methoxymatrine and 14-Aryloxymethylidenyl-Matrine Derivatives as Anti-HIV-1 Agents. Medicinal Chemistry, 14, 249-252. https://doi.org/10.2174/1573406413666171002120310
|
[27]
|
Qiu, S., Sun, H., Zhang, A.H., et al. (2014) Natural Alkaloids: Basic Aspects, Biological Roles, and Future Perspectives. Chinese Journal of Natural Medicines, 12, 401-406. https://doi.org/10.1016/S1875-5364(14)60063-7
|
[28]
|
Cushnie, T.P., Cushnie, B. and Lamb, A.J. (2014) Alkaloids: An Overview of Their Antibacterial, Antibiotic-Enhancing and Antivirulence Activities. International Journal of Antimicrobial Agents, 44, 377-386. https://doi.org/10.1016/j.ijantimicag.2014.06.001
|
[29]
|
Laxminarayan, R., Duse, A., Wattal, C., et al. (2013) Antibiotic Resistance—The Need for Global Solutions. The Lancet Infectious Diseases, 13, 1057-1098. https://doi.org/10.1016/S1473-3099(13)70318-9
|
[30]
|
Sharma, P., Gupta, S.K., Adenipekun, E.O., et al. (2020) Genome Analysis of Multidrug-Resistant Escherichia coli Isolated from Poultry in Nigeria. Foodborne Pathogens and Disease, 17, 1-7. https://doi.org/10.1089/fpd.2019.2659
|
[31]
|
Pourahmad, J.R. and Mohammadi, P. (2018) Effect of Total Alkaloid Extract of Local Sophora alopecuroides on Minimum Inhibitory Concentration and Intracellular Accumulation of Ciprofloxacin, and acrA Expression in Highly Resistant Escherichia coli Clones. Journal of Global Antimicrobial Resistance, 12, 55-60. https://doi.org/10.1016/j.jgar.2017.09.005
|
[32]
|
Zhou, X., Jia, F., Liu, X., et al. (2012) Total Alkaloids of Sophorea alopecuroides-Induced Down-Regulation of AcrAB-TolC Efflux Pump Reverses Susceptibility to Ciprofloxacin in Clinical Multidrug Resistant Escherichia coli Isolates. Phytotherapy Research, 26, 1637-1643. https://doi.org/10.1002/ptr.4623
|
[33]
|
Jia, F., Ma, W., Zhang, X., et al. (2020) Matrine and Baicalin Inhibit Apoptosis Induced by Panton-Valentine Leukocidin of Staphylococcus aureus in Bovine Mammary Epithelial Cells. Journal of Dairy Science, 103, 2731-2742. https://doi.org/10.3168/jds.2019-17619
|
[34]
|
Mohr, K.I. (2016) History of Antibiotics Research. Current Topics in Microbiology and Immunology, 398, 237-272. https://doi.org/10.1007/82_2016_499
|
[35]
|
Jin, H., Sun, Y., Wang, S., et al. (2013) Matrine Activates PTEN to Induce Growth Inhibition and Apoptosis in V600EBRAF Harboring Melanoma Cells. International Journal of Molecular Sciences, 14, 16040-16057. https://doi.org/10.3390/ijms140816040
|
[36]
|
Zhang, L., Wang, T., Wen, X., et al. (2007) Effect of Matrine on HeLa Cell Adhesion and Migration. European Journal of Pharmacology, 563, 69-76. https://doi.org/10.1016/j.ejphar.2007.01.073
|
[37]
|
Zhang, L.P., Jiang, J.K., Tam, J.W., et al. (2001) Effects of Matrine on Proliferation and Differentiation in K-562 Cells. Leukemia Research, 25, 793-800. https://doi.org/10.1016/S0145-2126(00)00145-4
|
[38]
|
Xing, Y., Yan, F., Liu, Y., et al. (2010) Matrine Inhibits T3-L1 Preadipocyte Differentiation Associated with Suppression of ERK1/2 Phosphorylation. Biochemical and Biophysical Research Communications, 396, 691-695. https://doi.org/10.1016/j.bbrc.2010.04.163
|
[39]
|
Zhou, B.G., Wei, C.S., Zhang, S., et al. (2018) Matrine Reversed Multidrug Resistance of Breast Cancer MCF-7/ADR Cells through PI3K/AKT Signaling Pathway. Journal of Cellular Biochemistry, 119, 3885-3891. https://doi.org/10.1002/jcb.26502
|
[40]
|
Liu, Y., Xu, Y., Ji, W., et al. (2014) Anti-Tumor Activities of Matrine and Oxymatrine: Literature Review. Tumor Biology, 35, 5111-5119. https://doi.org/10.1007/s13277-014-1680-z
|
[41]
|
Degterev, A., Boyce, M. and Yuan, J. (2003) A Decade of Caspases. Oncogene, 22, 8543-8567. https://doi.org/10.1038/sj.onc.1207107
|
[42]
|
Zhang, L. (2014) Molecular Mechanisms of Cell Cycle Arest and Proliferation Inhibition Induced by Aloperine in Human Cancer Cell HT29. Southern Medical University, Guangzhou.
|
[43]
|
Zhang, S., Zhang, Y., Zhuang, Y., et al. (2012) Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation. PLOS ONE, 7, e46853. https://doi.org/10.1371/journal.pone.0046853
|
[44]
|
Shao, Q., Zhao, X. and Yao, L. (2014) Matrine Inhibits the Growth of Retinoblastoma Cells (SO-Rb50) by Decreasing Proliferation and Inducing Apoptosis in a Mitochondrial Pathway. Molecular Biology Reports, 41, 3475-3480. https://doi.org/10.1007/s11033-014-3209-3
|
[45]
|
Jiang, W.G., Sanders, A.J., Katoh, M., et al. (2015) Tissue Invasion and Metastasis: Molecular, Biological and Clinical Perspectives. Seminars in Cancer Biology, 35, S244-S275. https://doi.org/10.1016/j.semcancer.2015.03.008
|
[46]
|
Liang, C.Z., Zhang, J.K., Shi, Z., et al. (2012) Matrine Induces Caspase-Dependent Apoptosis in Human Osteosarcoma Cells in Vitro and in Vivo through the Upregulation of Bax and Fas/FasL and Downregulation of Bcl-2. Cancer Chemotherapy and Pharmacology, 69, 317-331. https://doi.org/10.1007/s00280-011-1699-4
|
[47]
|
Zhang, Y., Zhang, H., Yu, P., et al. (2009) Effects of Matrine against the Growth of Human Lung Cancer and Hepatoma Cells as Well as Lung Cancer Cell Migration. Cytotechnology, 59, 191-200. https://doi.org/10.1007/s10616-009-9211-2
|
[48]
|
Ma, L., Zhu, Z., Jiang, L., et al. (2015) Matrine Suppresses Cell Growth of Human Chronic Myeloid Leukemia Cells via Its Inhibition of the Interleukin-6/Janus Activated Kinase/Signal Transducer and Activator of Transcription 3 Signaling Cohort. Leukemia & Lymphoma, 56, 2923-2930. https://doi.org/10.3109/10428194.2015.1007507
|
[49]
|
Liu, T., Song, Y., Chen, H., et al. (2010) Matrine Inhibits Proliferation and Induces Apoptosis of Pancreatic Cancer Cells in Vitro and in Vivo. Biological and Pharmaceutical Bulletin, 33, 1740-1745. https://doi.org/10.1248/bpb.33.1740
|
[50]
|
Hlobilkova, A., Ehrmann, J., Knizetova, P., et al. (2009) Analysis of VEGF, Flt-1, Flk-1, Nestin and MMP-9 in Relation to Astrocytoma Pathogenesis and Progression. Neoplasma, 56, 284-290. https://doi.org/10.4149/neo_2009_04_284
|
[51]
|
Yu, P., Liu, Q., Liu, K., et al. (2009) Matrine Suppresses Breast Cancer Cell Proliferation and Invasion via VEGF-Akt-NF-kappaB Signaling. Cytotechnology, 59, 219-229. https://doi.org/10.1007/s10616-009-9225-9
|
[52]
|
Yu, H.B., Zhang, H.F., Li, D.Y., et al. (2011) Matrine Inhibits Matrix Metalloproteinase-9 Expression and Invasion of Human Hepatocellular Carcinoma Cells. Journal of Asian Natural Products Research, 13, 242-250. https://doi.org/10.1080/10286020.2010.551641
|
[53]
|
Liu, X.Y., Fang, H., Yang, Z.G., et al. (2008) Matrine Inhibits Invasiveness and Metastasis of Human Malignant Melanoma Cell Line A375 in Vitro. International Journal of Dermatology, 47, 448-456. https://doi.org/10.1111/j.1365-4632.2008.03627.x
|
[54]
|
Levy-Adam, F., Ilan, N. and Vlodavsky, I. (2010) Tumorigenic and Adhesive Properties of Heparanase. Seminars in Cancer Biology, 20, 153-160. https://doi.org/10.1016/j.semcancer.2010.06.005
|
[55]
|
Shi, C., Yu, L., Yang, F., et al. (2003) A Novel Organoselenium Compound Induces Cell Cycle Arrest and Apoptosis in Prostate Cancer Cell Lines. Biochemical and Biophysical Research Communications, 309, 578-583. https://doi.org/10.1016/j.bbrc.2003.08.032
|
[56]
|
Zhao, B., Li, B., Bai, S., et al. (2012) Effects of Matrine on Proliferation and Apoptosis of Cultured Retinoblastoma Cells. Graefe’s Archive for Clinical and Experimental Ophthalmology, 250, 897-905. https://doi.org/10.1007/s00417-011-1751-4
|
[57]
|
Zhang, Z., Wang, X., Wu, W., et al. (2012) Effects of Matrine on Proliferation and Apoptosis in Gallbladder Carcinoma Cells (GBC-SD). Phytotherapy Research, 26, 932-937. https://doi.org/10.1002/ptr.3657
|
[58]
|
Zhu, P., Chen, J.M., Chen, S.Z., et al. (2010) Matrine Inhibits Vascular Smooth Muscle Cell Proliferation by Modulating the Expression of Cell Cycle Regulatory Genes. Acta Pharmacologica Sinica, 31, 1329-1335. https://doi.org/10.1038/aps.2010.145
|
[59]
|
Luo, S.X., Deng, W.Y., Wang, X.F., et al. (2013) Molecular Mechanism of Indirubin-3’-Monoxime and Matrine in the Reversal of Paclitaxel Resistance in NCI-H520/TAX25 Cell Line. Chinese Medical Journal (England), 126, 925-929.
|
[60]
|
Chai, S., To, K.K. and Lin, G. (2010) Circumvention of Multi-Drug Resistance of Cancer Cells by Chinese Herbal Medicines. Chinese Medicine, 5, 26. https://doi.org/10.1186/1749-8546-5-26
|
[61]
|
Zhang, J. and Tang, A.Z. (2012) Reversal Effect of Matrine on Drug Resistance of Human Nasopharyngeal Carcinoma Cell Line. Journal of Chinese Medicinal Materials, 35, 1989-1994.
|
[62]
|
Chen, H., Zhang, J., Luo, J., et al. (2013) Antiangiogenic Effects of Oxymatrine on Pancreatic Cancer by Inhibition of the NF-kappaB-Mediated VEGF Signaling Pathway. Oncology Reports, 30, 589-595. https://doi.org/10.3892/or.2013.2529
|
[63]
|
North, S., Moenner, M. and Bikfalvi, A. (2005) Recent Developments in the Regulation of the Angiogenic Switch by Cellular Stress Factors in Tumors. Cancer Letters, 218, 1-14. https://doi.org/10.1016/j.canlet.2004.08.007
|
[64]
|
Wang, Z., Zhang, J., Wang, Y., et al. (2013) Matrine, a Novel Autophagy Inhibitor, Blocks Trafficking and the Proteolytic Activation of Lysosomal Proteases. Carcinogenesis, 34, 128-138. https://doi.org/10.1093/carcin/bgs295
|
[65]
|
Liu, J., Zhang, L., Ren, Y., et al. (2016) Matrine Inhibits the Expression of Adhesion Molecules in Activated Vascular Smooth Muscle Cells. Molecular Medicine Reports, 13, 2313-2319. https://doi.org/10.3892/mmr.2016.4767
|
[66]
|
Lu, S. (2015) Matrine Inhibits IL-1b-Induced Expression of Matrix Metalloproteinases by Suppressing the Activation of MAPK and NFkB in Human Chondrocytes in Vitro. International Journal of Clinical and Experimental Pathology, 8, 4764-4772.
|
[67]
|
Wu, G., Zhou, W., Zhao, J., et al. (2017) Matrine Alleviates Lipopolysaccharide-Induced Intestinal Inflammation and Oxidative Stress via CCR7 Signal. Oncotarget, 8, 11621-11628. https://doi.org/10.18632/oncotarget.14598
|
[68]
|
Li, P., Lei, J., Hu, G., et al. (2019) Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis. Frontiers in Physiology, 10, 28. https://doi.org/10.3389/fphys.2019.00028
|
[69]
|
Gu, Y., Lu, J., Sun, W., et al. (2019) Oxymatrine and Its Metabolite Matrine Contribute to the Hepatotoxicity Induced by Radix Sophorae tonkinensis in Mice. Experimental and Therapeutic Medicine, 17, 2519-2528. https://doi.org/10.3892/etm.2019.7237
|
[70]
|
Guo, S., Gao, C., Xiao, W., et al. (2018) Matrine Protects Cardiomyocytes from Ischemia/Reperfusion Injury by Regulating HSP70 Expression via Activation of the JAK2/STAT3 Pathway. Shock, 50, 664-670. https://doi.org/10.1097/SHK.0000000000001108
|
[71]
|
Lu, Z.G., Li, M.H., Wang, J.S., et al. (2014) Developmental Toxicity and Neurotoxicity of Two Matrine-Type Alkaloids, Matrine and Sophocarpine, in Zebrafish (Danio rerio) Embryos/Larvae. Reproductive Toxicology, 47, 33-41. https://doi.org/10.1016/j.reprotox.2014.05.015
|
[72]
|
You, L., Yang, C., Du, Y., et al. (2019) Matrine Exerts Hepatotoxic Effects via the ROS-Dependent Mitochondrial Apoptosis Pathway and Inhibition of Nrf2-Mediated Antioxidant Response. Oxidative Medicine and Cellular Longevity, 2019, Article ID: 1045345. https://doi.org/10.1155/2019/1045345
|
[73]
|
You, L.T., Yang, C.J. and Leng, X. (2018) Study on the Toxicity of Matrine on HepaRG Cell Line. Global Traditional Chinese Medicine, 11, 1867-1874.
|
[74]
|
Liu, J., Zhao, Y., Xia, J., et al. (2020) Matrine Induces Toxicity in Mouse Liver Cells through an ROS-Dependent Mechanism Research in Veterinary Science, 132, 308-311. https://doi.org/10.1016/j.rvsc.2020.07.006
|
[75]
|
Wang, X.P. and Yang, R.M. (2003) Movement Disorders Possibly Induced by Traditional Chinese Herbs. European Neurology, 50, 153-159. https://doi.org/10.1159/000073056
|
[76]
|
Wang, X.Y., Liang, L., Chang, J.L., et al. (2010) Toxicity of Matrine in Kunming Mice. Journal of Southern Medical University, 30, 2154-2155.
|
[77]
|
Luo, T., Zou, Q.X., He, Y.Q., et al. (2016) Matrine Compromises Mouse Sperm Functions by a [Ca(2+)]I-Related Mechanism. Reproductive Toxicology, 60, 69-75. https://doi.org/10.1016/j.reprotox.2016.02.003
|
[78]
|
Luo, T., Zou, Q.X., He, Y.Q., et al. (2015) Matrine Inhibits Mouse Sperm Function by Reducing Sperm [Ca2+] and Phospho-ERK1/2. Cellular Physiology and Biochemistry, 35, 374-385. https://doi.org/10.1159/000369703
|
[79]
|
Zhang, Y. (2019) Matrine Attenuates High Glucose-Induced Podocyte Damage by Inhibiting HMGBl-Associated TLR4-NF-kappa B Signaling. International Journal of Clinical and Experimental Medicine, 7, 8512-8521.
|