The comparison of intravenous and lymphotropic routes of 99mTc ciprofloxacin in experimental pulmonary suppuration


Intravenously injected “99mTc-ciprofloxacin” is rapidly accumulated and washed from the septic focus. Lymphotropic injections provide targeted and long-lasting effect of antibiotics. After injection into the interspinous ligament the drug slowly enters the inflammation area (by-passing the urinary organs and liver), where it is maximally accumulated only after 24 h, which allows to reduce the number of injections and the total dose of the antibiotic.

Share and Cite:

Lishmanov, Y. , Sazonova, S. , Sokolovich, Y. and Chernov, V. (2011) The comparison of intravenous and lymphotropic routes of 99mTc ciprofloxacin in experimental pulmonary suppuration. Health, 3, 663-667. doi: 10.4236/health.2011.311111.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Borodin, Yu.I., Lubarskiy, Yu.I., Lubarskiy, M.S., Efremov, A.V., et al. (1997) The pathogenetic approaches. SD RАМS, Novosibirsk.
[2] Borodin, Yu.I., Trufakin, V.A., Lubarskiy, M.S., et al. (2001) Clinical lymphology essays. SD RАМS, Novosi- birsk.
[3] Panchenkov, R.T., Vyrenkov, Yu.E., Yarema, I.V. and Scherbakova, E.G. (1984) The endolymphatic antibiotic therapy. Medicina, Мoscow.
[4] Levin, Yu.M. (1986) Principles of medicinal lymphology. Medicina, Мoscow.
[5] Levin, Yu.M., Muradov, R.G., Samoylova, Е.V. and Sviridkina, L.P. (1996) Problems of experimental and clinical lymphology. Publishing of the Research Institute of Clinical and Experimental Lymphology, Novosibirsk.
[6] Lubarskiy, M.S. and Shevela, A.I. (2001) The limbs lymphedema. SD RАМS, Novosibirsk.
[7] Britton K. E., Vinjamuri S., Hall A. V., et al. (1997) Clinical evaluation of technetium-99 m infecton for the localisation of bacterial infection. European Journal of Nuclear Medicine and Molecular Imaging, 5, 553-556.
[8] Shalimov, S.А., Radzihovsky, А.P. and Keysevich, L.V. (1989) Experimental surgery guidance. Medicina, Мos- cow.
[9] Cyb, A.F., Zubovsky, A.F. and Gabunia, R.F. (1987) Standardized methods of radionuclide diagnostics (guide- lines). Obninsk.

Copyright © 2021 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.