Diabetic lipemia associated with acute pancreatitis in a patient with type 2 diabetes
Daisuke Ogawa, Jun Wada, Hirofumi Makino
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DOI: 10.4236/jdm.2011.13008   PDF    HTML   XML   7,081 Downloads   11,203 Views   Citations

Abstract

We report a 59-year-old man with diabetic lipemia associated with acute pancreatitis. The patient was being treated for type 2 diabetes, but his glycemic control was poor. Although his insulin secretory activity was preserved, acute pancreatitis developed because of hypertriglyceridemia and the patient had type V hyperlipidemia. After hospitalization, his hyperlipidemia and hyperglycemia improved in response to insulin infusion and hydration. It is well known that diabetic lipemia is caused by type 1 diabetes, but is rare in type 2 diabetes. Insulin resistance, as well as insulin deficiency, might play a role in the development of diabetic lipemia.

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Ogawa, D. , Wada, J. and Makino, H. (2011) Diabetic lipemia associated with acute pancreatitis in a patient with type 2 diabetes. Journal of Diabetes Mellitus, 1, 54-56. doi: 10.4236/jdm.2011.13008.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Bagdade, J.D., Porte, D. Jr. and Bierman, E.L. (1967) Diabetic lipemia. A form of acquired fat-induced lipemia. The New England Journal of Medicine, 276, 427-433. doi:10.1056/NEJM196702232760802
[2] Howard, B.V. (1987) Lipoprotein metabolism in diabetes mellitus. The Journal of Lipid Research, 28, 613-628.
[3] Chait, A., Robertson H.T. and Brunzell J.D. (1981) Chylomicronemia syndrome in diabetes mellitus. Diabetes Care, 4, 343-348. doi:10.2337/diacare.4.3.343
[4] Tsuang, W., Navaneethan U., Ruiz L., Palascak J.B. and Gelrud, A. (2009) Hypertriglyceridemic pancreatitis: Presentation and management. The American Journal of Gastroenterology, 104, 984-991. doi:10.1038/ajg.2009.27
[5] Winter, R.J., Herr, T.J., Stone, N.J. and Traisman, H.S. (1980) Diabetic lipemia in childhood diabetic ketoacidosis: A clue to coexisting acute pancreatitis. Diabetes Care, 3, 706-707.
[6] Nair, S., Yadav, D. and Pitchumoni, C.S. (2000) Association of diabetic ketoacidosis and acute pancreatitis: Observations in 100 consecutive episodes of DKA. The American Journal of Gastroenterology, 95, 2795-2800. doi:10.1111/j.1572-0241.2000.03188.x
[7] Chen, J.L., Spinowitz, N. and Karwa, M. (2003) Hypertriglyceridemia, acute pancreatitis, and diabetic ketoacidosis possibly associated with mirtazapine therapy: A case report. Pharmacotherapy, 23, 940-944. doi:10.1592/phco.23.7.940.32725
[8] Haddad, N.G., Croffie, J.M. and Eugster, E.A. (2004) Pancreatic enzyme elevations in children with diabetic ketoacidosis. Journal of Pediatrics, 145, 122-124. doi:10.1016/j.jpeds.2004.03.050

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