Controlling fusarium head blight of wheat (triticum aestivum L.) with genetics
Li Zhang, Peigao Luo, Zhenglong Ren, Huai-yu Zhang
DOI: 10.4236/abb.2011.24038   PDF   HTML     5,772 Downloads   12,682 Views   Citations


Fusarium head blight, one of the most destructive diseases of wheat (Triticum aestivum L.), results in significant economic losses from reduced grain yield and quality. In recent decades, the disease has been frequently recorded, especially under warm and wet climatic conditions. Genetic resistance has engaged plant breeders because the use of resistant cultivars is the most economical, effective, and environmentally friendly method of control. In the present paper, we summarize the research on resistance genetics of Fusarium head blight, suggest a new method for evaluating Fusarium head blight resistance, and recommend strategies for creating and developing new sources of resistance to Fusarium head blight through the use of alien genes and chromosomal segments.

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Zhang, L. , Luo, P. , Ren, Z. and Zhang, H. (2011) Controlling fusarium head blight of wheat (triticum aestivum L.) with genetics. Advances in Bioscience and Biotechnology, 2, 263-270. doi: 10.4236/abb.2011.24038.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Parry, D.W., Jenkinson, P., and Mcleod, L. (1995) Fusarium ear blight (scab) in small grain cereal-a review. Plant Pathology, 44(2), 207-238.
[2] Walter, S., Nicholson, P., and Doohan, F.M. (2010) Action and reaction of host and pathogen during Fusarium head blight disease. New Phytologist, 185(1), 54-66.
[3] Bai, G.H., and Shaner, G. (1994) Scab of wheat: prospects for control. Plant Disease, 78(8), 760-766.
[4] Stepień, L., and Chelkowski, J. (2010) Fusarium head blight of wheat:pathogenic species and their mycotoxins. World Mycotoxin Journal, 3(2), 107-119.
[5] Li, X., Zhang, J.B., Song, B., Li, H.P., Xu, H.Q., and Qu B., et al. (2010) Resistance to fusarium head blight and seedling blight in wheat is associated with activation of a cytochrome P450 gene. Phytopathology, 100(2), 183-191.
[6] Mesterhazy, A. (1995) Types and components of resistance to Fusarium head blight of wheat. Plant Breeding, 114(5), 377-386.
[7] Miedaner, T. (1997) Breeding wheat and rye for resistance to Fusarium disease. Plant Breeding, 116(3), 201-220.
[8] Xu, X.M., and Nicholson, P. (2009) Community ecology of fungal pathogens causing wheat head blight. Annual Review of Phytopathology, 47, 83-103.
[9] Snijders, C.H.A. (1990) The inheritance of resistance to head blight caused by Fusarium culmorum in winter wheat. Euphytica, 50(1), 11-18.
[10] Placinta, C.M., D’Mello, J.P.F., and Macdonald, A.M.C. (1999) A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Animal Feed Science Technical, 78(1-2), 21-37.
[11] Mesterhazy, A., Bartok, T., Mirocha, C.G., and Komorozy, R. (1999) Nature of wheat resistance to Fusarium head blight and role of Deoxynivalenol for breeding. Plant Breeding, 118(2), 7-110.
[12] Kolb, F.L., Bai, G.H., Muehlbauer, G.J., Anderson, J.A., Smith, K.P. and Fedak, G. (2001) Host plant resistance genes for Fusarium head blight:mapping and manipulation with molecular markers. Crop Science, 41(3), 611-619.
[13] Cai, X., Chen, P.D., Xu, S.S., Oliver, R.E. and Chen, X. (2005) Utilization of alien genes to enhance Fusarium head blight resistance in wheat-a review. Euphytica, 142(3), 309-318.
[14] Anderson, J.A. (2007) Marker-assisted selection for Fusarium head blight resistance in wheat. Internation Journal of Food Microbiology, 119(1-2), 51-53.
[15] Buerstmary, H., Ban, T., and Anderson, J.A. (2009) QTL mapping and marker-assisted slection for Fusarium head blight resistance in wheat: a rivew. Plant Breeding, 128(1), 1-26.
[16] Rossi, V., Ravanetti, A., Pattori, E., and Giosue, S. (2001) Influence of temperature and humidity on the infection of wheat spikes by some fungi causing Fusarium head blight. Journal of Plant Pathology, 83(3), 189-198.
[17] Adams, J.F. (1921) Observations on wheat scab in Pennsylvania and its pathological histology. Phytopathology, 11, 115-125.
[18] Arthur, J.C. (1891) Wheat scab. Indinan Agri. Exp. Stn. Bull, 36, 129-138.
[19] Warren, H.L., and Kommedahl, T. (1973) Fertilization and wheat refuse effects on Fusarium species associated with wheat roots in Minnesota. Phytopathology, 63, 103-108.
[20] Sutton, J.C. (1982) Epidemiology of wheat head blight and maize ear rot caused by Fusarium graminearum. Canadian Journal of Plant Pathology, 4(2), 195-209.
[21] Snyder, W.C., and Nash, S.M. (1968) Relative incidence of Fusarium pathogens of cereals in rotation plots at Rothamsted. Transactions of the British Mycological Society, 51, 17-25.
[22] Hoffer, G.N., Johnson, A.G., and Atanasoff, D. (1918) Corn root rot and wheat scab. Journal of Agriculture Research, 14, 611-612.
[23] Seaman, W.L. (1982) Epidemiology and control of mycotoxingenic Fusaria on cereal grains. Canadian Journal of Plant Pathology, 4, 187-190.
[24] Zhu, H., and Fan, Y. (1989). Wheat scab epidemics and efficacy of testing for resistance in field in northern Fujiang Province. Jounal of Jiangsu Agricuture Science, 1, 75-78.
[25] Paul, P.A., El-Allaf, S.M., Lipps, P.E., and Madden, L.V. (2004) Rain splash dispersal of Gibberella zeae wheat canopies in Ohio. Phytopathology, 94(12), 1342-1349.
[26] Hart, L., Pestka, J., and Liu, M. (1984) Effect of kernel development and wet periods on production of deoxynivalenol in wheat infected with gibberella zeae. Phytopathology, 74(2), 1415-1418.
[27] Del Ponte, E.M., Fermandes, J.M.C., and Bergstrom, G.C. (2007) Influence of growth stage on fusarium head blight and deoxynivalenol production in wheat. Journal of Phytopathology, 155(10), 577-581
[28] Pugh, G.W., Johann, H., and Dickson, J.G. (1933) Factors affecting infection of wheat heads by Gibberella saubinetii. Journal of Agriculture Reseach, 46, 771-791.
[29] Horberg, H. (2002) Patterns of splash dispersed conidia of fusarium poae and fusarium culmorum. European Journal of Plant Pathologhy, 108(1),73-80.
[30] Paul, P.A., Lipps, P.E., Hershman, D.E., McMullen, M.P., Draper, M.A. and Madden, L.V. (2007) A quantitative review of tebuconazole effect on Fusarium head blight and deoxynivalenol content in wheat. Phytopathology, 97(2), 211-220.
[31] Matthies, A., and Buchenauer, H. (2000) Effect of tebuconazole(Folicur) and prochloraz(Sportac) treatments on Fusarium head scab development, yield and deoxynivalenol(DON) content in grains of wheat following artificial inoculation with Fusarium culmorum. Zeitschrift Für Pflanzenkrankheiten Und Pflanzenschutz, 107(1), 33-52.
[32] Wang, Y.Z., Yong, X.N., and Xiao, Q.P. (1982) The improvement of identification techniques of scab resistance of wheat and development of resistant sources. Scientica Agricultura Sinica, 5, 67-7.
[33] Lu, W.Z., Chen, S.H., and Wang, Y.Z. (2001) Reserch on wheat scab. Science Publication House Press Inc Beijing, China.
[34] Windels, C.E. (2000) Economic and social impacts of Fusarium head blight: Changing farm and rural communities in the Northern Great Plains. Phytopathology, 90(1), 17-21.
[35] Mesterhazy, A. (1987) Selection of head blight resistant wheats through improved seedling resistance. Plant Breeding, 98(1), 23-36.
[36] Snijders, C.H.A. (1990) Fusarium head blight and mycotoxin contamination of wheat, a review. European Journal of Plant Pathology, 96(4), 187-198.
[37] Zhang, Y.J., Fan, P.S., Zhang, X., et al. (2009) Quantification of Fusarium greminearum in harvested grain by real–time polymerase chain reactin to assess efficacies of Fungicides on Fusarium head blight ,deoxynivalenol contamination, and yield of winter wheat. Pathology, 99(1), 95-100.
[38] Kang, Z., and Buchenauer, H. (1999) Immunocytochemical localization of Fusarium toxins in infected wheat spikes by Fusarium culmorum. Physiology Molecule Plant Pathology, 55(5), 257-288.
[39] Culler, M.D., Miller-Garvin, J.E., and Dill-Macky, R. (2007) Effect of extended irrigation and host resistance on deoxynivalenol accumulation in Fusarium-infected wheat. Plant Disease, 91(1), 1464-1472.
[40] Cowger, C., Patton-?zkurt, J., Brown-Guedira, G., et al. (2009) Post-anthesis increased Fusarium head blight and deoxynivalenol levels in North Carolina winter whaet. Phytopathology, 99(4), 320-327.
[41] Lemmens, M., Scholz, U., Berthiller, F., et al. (2004) The role of resistance to deoxynivalenol in the complex Fusarium head blight resistance complex in wheat. In: Canty S.M., T. Boring, J. Wardwell, R.W. Wards (eds). Proceeding of 2nd Int. Symp. Fusarium Head Blight. 2004, East Lansing:88.
[42] Langevin, F., Eudes, F., and Comeau, A. (2004) Effect of tricothecenesn produced by Fusariu graminearum during Fusarium head blight development in six cereal species. Europeaon Journal of Plant Pathology, 110(7), 735-746.
[43] Pestka, J.J., Zhou, H.R., Moon, Y., et al. (2004) Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. Toxicology Letters, 153(1), 61-73.
[44] Schollenberger, M., Muller, H.M., Rufle, M., et al. (2005) Survey of Fusarium toxins in foodstuffs of plant origin marketed in Germany. International Journal of Food Microbiology, 97(3), 317-326.
[45] Nishio, Z., Takata, K., Ito, M., Tanio, M., Tabiki, T., and Yamauchi, H., et al. (2010) Deoxynivalenol distribution in flour and bran of spring wheat lines with different levels of Fusarium head blight resistance. Plant Disease, 94(3), 335-338.
[46] Gilbert, J., Conner, R., Femandez, M., McLaren, D. and Woods, S. (2003) Role of spring wheat infested with fusarium graminearum in spread and development of fusarium head blight and effects on agronomic performance. Journal of Plant Pathology, 25(1), 73-81.
[47] Paul, P., Lipps, P., Hershman, D., McMullen, M., Draper, M. and Madden, L. (2008) Efficacy of triazole-based fungicides for fusarium head blight and deoxynivalenol control in wheat:a multivariate meta-analysis. Phytopathology, 98(9), 999-1011.
[48] Pirgozliev, S., Ray, R., Edwards, S., Hare, M. and Jenkinson, P. (2008) Effect of timing of fungicide application on the development of fusarium head blight and the accumulation of deoxynivalenol (DON) in winter wheat grain. Cereal Research Communications, 36(2), 289-299.
[49] Blandino, M., and Reyneri, A. (2009) Effect of fungicide and foliar fertilizer application to winter wheat at anthesis on flag leaf senescence, grain yield,flour bread-making quality and DON contamination. European Journal of Agronomy, 30(4), 275-282.
[50] Siranidou, E., and Buchenauer, H. (2001) Chemical control of Fusarium head blight on wheat. Journal of Plant Disease Protection, 108(3), 231-234.
[51] Wiersma, J.J., and Motteberg, C.D. (2005) Evaluation of five fungicide application timings for the control of leaf-spot diseases and Fusariunhead blight in hard red spring wheat. Canadian Journal of Plant Pathology, 27(1), 25-27.
[52] Miller, J.D., and Trenholm, H.L. (1994) Mycotoxins in Grains. Eagan Press Inc St. Paul, Minnesota.
[53] Wolf-Hall, C.E. (2007) Mold and mycotoxin problems encountered during malting and brewing. International Journal of Food Microbiology, 119(1-2), 89-94.
[54] Gilbert, J., and Tekauz, A. (2000) Review: recent developments in research on Fusarium head blight of wheat in Canada. Canadian Journal of Plant Pathology, 22(1), 1–8.
[55] Del Blanco, I.A., Frohberg, R.C., Stack, R.W., Berzonsky, W.A., and Kianian, S.F. (2003) Detection of QTL linked to Fusarium head blight resistance in Sumai 3-derived North Dakota bread wheat lines. Theoretica and Applied Genetics, 106(6), 1027–1031.
[56] Rudd, J.C., Horsley, R.D., McKendry, A.L., and Elias, E.M. (2001) Host plant resistance genes for Fusarium head blight: sources, mechanisms, and utility in conventional breeding systems. Crop Science, 41(3), 620–627.
[57] Lin, F., Kong, Z.X., Zhu, H.L., Xue, S.L., Wu, J.Z., and Tian, D.G., et al. (2004) Mapping QTL associated with resistance to Fusarium head blight in the Nanda2491 × Wangshuibai population.I. Type II resistance. Theoretical and Applied Genetics, 109(7), 1504-1511.
[58] Schroeder, H.W., and Christensen, J.J. (1963) Factors affecting resistance of wheat scab caused by gibberella zeae. Phytopathology, 53, 831-838.
[59] Miller, J., and Arnison, P. (1986) Degradation of deoxynivalenol by suspension culture of the fusarium head blight resistant wheat cultivar frontana. Canadian Journal of Plant Patholog, 8(2), 147-150.
[60] Wang, Y.Z., and Miller, J. (1988) Effects of fusarium-graminearum metabolites on wheat tissue in relation to fusarium head blight resistance. Journal of Phytopathology, 122(2), 118-125.
[61] Bai, G., Desjardins, A.E., and Plattner, R.D. (2001) Deoxynivalenol-nonproducing fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. Mycopathologia, 153(2), 91-98.
[62] Eudes, F., Comeau, A., Rioux, S., et al. (2001) Impact of trichothecenes on fusarium head blight [Fusarium graminearum] development in spring wheat (triticum aestivum). Canadian Journal of Plant Pathology, 23, 318-322.
[63] Jansen, C, von Wettstein, D., Schafer, W., et al. (2005) Infection patterns in barley and wheat spikes inoculated with wild-type and trichodiene synthase gene disrupted fusarium graminearum. Proceedings of the National Academy of Sciences of the United States of America, 102(46), 16892-16897.
[64] Wojciechowski, S., Chelkowski, J., and Kostecki, M. (1995) Infulence of dexoynivalenol on electrolyte Leakage in cereal seeding leaves. Acta Physiologiae Plantarum, 17(4), 357-360.
[65] Miller, J.D., and Ewen, M.A. (1997) Toxic effects of deoxynivalenol on ribosomes and tissues of the spring wheat clutivars Frontana and Casavant. Nature Toxins, 5(6), 234-237.
[66] Friebe, A., Vilich, V., Hennig, L., Kluge, M. and Sicker, D. (1998) Detoxification of benzoxazolinone allelochemicals from wheat by Gaeumannomyces graminis var. tritici, G. graminis var. graminis, G.graminis var. avenae, and Fusarium culmorum. Applied Enviromental Microbiology, 64(7), 2386-2391.
[67] McKeehen, J.D., Busch, R.H., and Fulcher, R.G. (1999) Evaluation of wheat ( Triticum aestivum L.) phenolic acids during grain development and their contribution to Fusarium resistance. Journal of Agricultural and Food Chemistry, 47(4), 1476-1482.
[68] Bai, G.H., Zhou, C.F., Qian, C.M., et al. (1989) An analysis on combining ability of resistance to scab and other characters in eight wheat cultivars. Journal of Jiansu Agricalture Science, 1, 79-83.
[69] Mujeeb-Kazi, A., Bernard, M., Bekele, G.T., and et al. (1983) Incorporation of alien genetic information from Elymus giganteus into Triticum aestivum. In: S.Sakamoto(Ed), Proc 6th Int Wheat Genet Symp Maruzen, Kyoto, Japan. pp. 223-231.
[70] Wang, Y.N., Chen, P.D., and Liu, D.J. (1986) Transfer of useful germplasm from Elymus giganteus L. to Commom wheat .I. Production of (T. aestivum L. cv. Chinese Spring x E. giganteus) F1. Joural of Nangjing Agriculture University,1(1), 10-14.
[71] Wang, Y.N., Chen, P.D., Wang, Z.T., et al. (1991) Transfer of useful germplasm from Elymus giganteus L. to commom wheat. II. Cytogenetics and scab resistance of backcross derivatives. Joural of Nangjing Agriculture University, 14, 1-5.
[72] Wan, Y.F., Yen, C., and Yang, J.L. (1997) The diversity of head-scab resistance in Triticeae and their relation to ecological conditions. Euphytica, 97(3), 277-281.
[73] Fedak, G. (2000) Sources of resistance to Fusarium head blight. Proceeding of the Int Symp Wheat Improv Scab Resist, 2000, Nangjing, 4.
[74] Oliver, R.E., Cai, X., Xu, S.S., and Stack, R.W. (2005) Wheat-alien species derivatives: a novel source of Resistance to Fusarium head blight in wheat. Crop Science, 45(4), 1353-1360.
[75] Ban, T. (1997) Evaluation of resisitance to Fusarium head blight in indigenous Japanese species of Agropyron(Elymus). Euphytica , 97(1), 39-44.
[76] Han, F.P., Fedak, G., Benbdelmouna, A., Armstrong, K. and Ouellet, T. (2003) Characterization of six wheat × Thinopyrum intermedium derivatives by GISH, RFLP, and Multicolor GISH. Genome, 46(3), 490-495.
[77] Shen, X., Kong, L., and Ohm, H. (2004) Fusarium head blight resistance in hexaploid wheat (Triticum asetivum)-Lophopyrum genetic lines and tagging of the alien chromatin by PCR markers. Theoretical and Applied Genetics, 108(5), 808-813.
[78] Steed, A., Chandler, E., Thomsett, M., Gosman, N., Faure, S. and Nicholson, P. (2005) Identification of Type I resistance to Fusarium head blight controlled by a major gene located on chromosome 4A of Tritium macha. Theoretical and Applied Genetics, 111(3), 521-529.
[79] Chen, P.D., Liu, W.X. , Yuan, J.H., Wang, X., Zhou, B., and Wang, S.L., et al. (2005) Development and characterization of wheat-Leymus racemosus translocation lines with resistance to Fusarium Head Blight. Theoretica and Applied Genetics, 111(5), 941-948.
[80] Cai, X., Xu, S.S., Oliver, R.E., Zhang, Q., Stack, R.W., and Zhong, S., et al. (2008) Alien introgression for FHB resistance in wheat-challenges and strategies. In: Appels R., R. Eastwood, E. Lagudah, P. Langridge, M. Mackay, L. McIntye and P. Sharp (ed). Proceeding of the 11th Wheat Genet, Sydney, 716-718.
[81] Ren, Z.L., Zhang, H.Q. (1997) Induction of small-segment-translocation between wheat and rye chromosomes. Science in China (Series C), 40(3), 322-331.
[82] Multani, D.S., Jena, K.K., and Brar, D.S. (1994) Development of monosomic alien addition lines and introgress of genes from Oryza-australiensis domin to cultivated rice Oryza-sativa L. Theoretical and Applied Genetics, 88(1), 102-109.
[83] Kuraparthy, V., Sood, S., Chhuneja, P., Dhaliwal, H.S., Kaur, S., and Bowden, R.L., et al. (2007) A cryptic wheat-Aegilops triuncialis translocation with leaf rust resistance gene Lr58. Crop Science, 47(5), 1995-2003.
[84] Zamir, D. (2001) Improving plant breeding with exotic genetic libraries. Nat Rev Genet, 2, 983-989
[85] Ma, Q., Luo, P.G., Ren, Z.L., Jiang H.R., Yang Z.J. (2007) Genetic analysis and chromosoma location of two new genes for resistance to powdery mildew in wheat (Triticum aestivum L.). Acta Agronomica Sinica, 33(1), 1–8.
[86] Luo, P.G., Luo, H.Y., Chang, Z.J., Zhang, H.Y., Zhang, M., Ren Z.L. (2009) Characterization and chromosomal location of Pm40 in common wheat:A new gene for resistance to powdery mildew derived from Elytrigia intermedium. Theoretical and Applied Genetics, 118(6), 1059-1064.
[87] Luo, P.G., Hu, X.Y., Chang, Z.J., et al. (2009) A new stripe rust resistance gene transferred from Thinopyrum intermedium to hexaploid wheat. Phytoprotection, 90, 57-63.
[88] Zhang, L., Chen, J.B., Yang, J.Z., et al. (2009) Identification of new germplasm of wheat scab resistance. Prcoreeding of the Crop science society of China 2009 annual conference proceedings. Guang zhou 2009:143.
[89] Krattinger, S.G., Lagudah, E.S., Spielmeyer, W., Singh, R.P., Huerta-Espino, J., and McFadden, H. et al. (2009) A putative ABC transporter confers durable resistance to multiple fun gal pathogens in wheat. Science, 323(5919), 1360-1363.

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