Testicular Lipomatosis without Evidence of Cowden’s Disease


Background: Testicular lipomatosis is a very rare and benign disorder of the testicles. It usually presents as multiple bilateral ill-defined hyper-echoic intra-testicular lesions of different sizes but generally with maximum 4 mm. Testicular lipomatosis is usually reported in association with Cowden’s syndrome. Aim: We aimed to show that there are cases of testicular lipomatosis occurring in the absence of Cowden’s syndrome. Case Presentation: We present a 28-year-old man with testicular pain, who was finally diagnosed as having isolated testicular lipomatosis without other clinical and biochemical abnormalities using magnetic resonance imaging (MRI) technique. Conclusion: We showed that the testicular lipomatosis may occur and be detected without any evidence of Cowden’s disease.

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Azandariani, A. , Ebrahimi, L. and Saedi, S. (2015) Testicular Lipomatosis without Evidence of Cowden’s Disease. Case Reports in Clinical Medicine, 4, 364-368. doi: 10.4236/crcm.2015.412074.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Ulbright, T.M., Srigley, J.R., Hatzianastassiou, D.K., et al. (2002) Leydig Cell Tumors of the Testis with Unusual Features. Adipose Differentiation, Calcification with Ossification, and Spindle-Shaped Tumor Cells. American Journal of Surgical Pathology, 26, 1424-1433.
[2] Venkatanarasimha, N., Hilmy, S. and Freeman, S. (2011) Case 175: Testicular Lipomatosis in Cowden Disease. Radiology, 261, 654-658.
[3] Woodhouse, J.B., Delahunt, B., English, S.F., Fraser, H.H. and Ferguson, M.M. (2005) Testicular Lipomatosis in Cowden’s Syndrome. Modern Pathology, 18, 1151-1156.
[4] Lindsay, C., Boardman, L. and Farrell, M. (2003) Testicular Hamartomas in Cowden Disease. Journal of Clinical Ultrasound, 31, 481-483.
[5] Woodhouse, J. and Ferguson, M.M. (2006) Multiple Hyperechoic Testicular Lesions Are a Common Finding on Ultrasound in Cowden Disease and Represent Lipomatosis of the Testis. The British Journal of Radiology, 79, 801-803.

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