The Efficacy of Tocilizumab for Takayasu Arteritis: Review of the Literatures
Nesibe Karahan Yeşil1, Hatice Şahin2, Metin Işik3*, Ziyaeddin Aktop4, İsmail Doğan5, Ali Erdem Baki6
1Department of Rheumatology, Ankara Research and Education Hospital, Ankara, Turkey.
2Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
3Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Mevlana University, Konya, Turkey.
4Department of Cardiology, Bülent Ecevit University, Zonguldak, Turkey.
5Division of Rheumatology, Department of Internal Medicine, Çorum Hitit University, Çorum, Turkey.
6Department of Physical Medicine and Rheabilitation, Bülent Ecevit University, Zonguldak, Turkey.
DOI: 10.4236/ojra.2015.54019   PDF   HTML   XML   3,679 Downloads   4,514 Views   Citations


Takayasu arteritis is a large vessel vasculitis of the young women with giant cells and granuloma formation. The diagnosis and management of the disease are really not so easy because of the insidious onset and the difficulties in assessment of disease activity. Nearly 60% of the patients are corticosteroid resistant or dependent and relapses are very frequent during taper of the dose [1]. The novel biologic agents as Anti-TNF, Rutiximab and Tocilizumab provide acceptable response rates with low toxicity. Herein, we reviewed the efficacy of Tocilizumab in Takayasu arteritis.

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Yeşil, N. , Şahin, H. , Işik, M. , Aktop, Z. , Doğan, İ. and Baki, A. (2015) The Efficacy of Tocilizumab for Takayasu Arteritis: Review of the Literatures. Open Journal of Rheumatology and Autoimmune Diseases, 5, 118-125. doi: 10.4236/ojra.2015.54019.

Conflicts of Interest

The authors declare no conflicts of interest.


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