Umbilical Cord Blood CD33 and Erythropoietin Levels of Pregnants with Abnormal Doppler Waveforms and to Compare with Normal Pregnancies

Nilay Karaca^1*, Gökhan Bolluk², Yaşam Kemal Akpak³, Aslıhan Erken⁴, Serkan Oral⁵

¹Department of Obstetrics and Gynecology, Bezmi Alem Vakif University, Medical Faculty, Istanbul, Turkey.
²Department of Obstetrics and Gynecology, Lütfiye Nuri Burat State Hospital, Istanbul, Turkey.
³Department of Obstetrics and Gynecology, Ankara Mevki Military Hospital, Ankara, Turkey.
⁴Department of Obstetrics and Gynecology, Bayrampasa State Hospital, Istanbul, Turkey.
⁵Department of Assisted Reproduction, LIV Hospital, Istanbul, Turkey.

DOI: 10.4236/ojog.2015.54034                

Abstract

Objective: In this study, we aimed to investigate umbilical cord blood CD33 and erythropoietin (EPO) levels of pregnants with abnormal umbilical and uterine artery doppler waveforms and to compare with normal pregnancies. Materials and Methods: Total 40 pregnant women were included in this study. Of these 40 women, while 20 patients had abnormal umbilical and uterine artery doppler waveforms, the other 20 patients had normal umbilical and uterine artery doppler waveforms. After the delivery, blood samples were taken from umbilical artery of double clemped umbilical cord for blood gas parameters, EPO and CD33 levels. Sociodemographic findings, antepartum, intrapartum test results, labor and delivery characteristics and newborn examination results were recorded. Blood gas parameters, EPO and CD33 levels between groups were analyzed. Mann-Whitney U test and t-test were used as statistical methods. Results: There were no differences between parity, gestational ages and newborn weights of the groups. Cord blood CD33 and EPO levels of group with abnormal umbilical and uterine artery doppler waveforms were significantly higher than group with normal umbilical and uterine artery doppler waveforms (p < 0.01). Conclusion: Pathology on doppler screen shows to us a connection between chronic hypoxemia and abnormal on doppler screen. Preference of high blood CD33 levels for cord blood transplantation especially during last years can also be used with preference of cord blood with abnormal doppler findings.

Keywords

Antenatal Care, CD33, Doppler Ultrasonography, Erythropoietin, Perinatology, Umbilical Cord Blood

Conflicts of Interest

The authors declare no conflicts of interest.

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