Morphology Control of Polymer Microspheres Containing Block Copolymers with Seed Polymerization

DOI: 10.4236/ojopm.2015.52005   PDF   HTML   XML   4,487 Downloads   5,226 Views   Citations


Microspheres based on binary polymer blend consisting of polystyrene (PSt), poly (methyl methacrylate) (PMMA), block copolymer comprising PSt and PMMA subunits, and ternary polymer blend consisting of PSt, PMMA, and block copolymer were fabricated by a solvent evaporation method, in which a polymer solution in dichloromethane was dispersed in water phase with the aid of a homogenizer to obtain an O/W emulsion followed by solvent evaporation with agitation to solidify the polymer. In the case of ternary blend, the effect of block copolymer content on the morphology of resulting spheres was investigated. Ternary blends afforded the bi-compartmental morphologies, the intermediate morphology between Janus and core-shell, which was confirmed by TEM observation. Seed polymerization of St or MMA was also carried out utilizing the resulting microspheres as seed particles in order to control the shape, and the surface morphology of particles. The particles with snowman-like morphology were obtained by seed polymerization of St using PSt/PMMA binary blend microspheres as seed particles. Surface roughness was controlled by the polymerization of MMA in the block copolymer seed, and that of St in the ternary blend seed.

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Taherzadeh, H. , Sotowa, S. and Ogino, K. (2015) Morphology Control of Polymer Microspheres Containing Block Copolymers with Seed Polymerization. Open Journal of Organic Polymer Materials, 5, 43-50. doi: 10.4236/ojopm.2015.52005.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Pancholi, K., Ahras N., Stride E. and Edirisinghe, M. (2009) Novel Electrohydrodynamic Preparation of Porous Chitosan Particles for Drug Delivery. Journal of Material Science: Material in Medicine, 20, 917-923.
[2] Xie, J., Huang, J., Li, X., Sun, S. and Chen, X. (2009) Iron Oxide Nanoparticle Platform for Biomedical Applications. Current Medical Chemistry, 16, 1278-1294.
[3] Perrier-Cornet, R., Heroguez, V., Thienpont, A., Babot, O. and Toupance, T. (2008) Functional Crosslinked Polymer Particles Synthesized by Precipitation Polymerization for Liquid Chromatography. Journal of Chromatography A, 1179, 2-8.
[4] Garnett, M.C., Ferruti, P., Ranucci, E., Suardi, M.A., Heyde, M. and Sleat, R. (2009) Sterically Stabilized Self-As- sembling Reversibly Cross-Linked Polyelectrolyte Complexes with Nucleic Acids for Environmental and Medical Applications. Biochemical Society Transactions, 37, 713-716.
[5] He, Y., Daniel, E.S., Klein, A. and El-Aasser, M.S. (1997) Grafting Behavior of n-Butyl Acrylate onto Poly(butadiene- co-styrene) Latexes. Journal of Applied Polymer Science, 65, 511-523.
[6] Joensson, J.E., Hassander, H. and Toernell, B. (1994) Polymerization Conditions and the Development of a Core-Shell Morphology in PMMA/PS Latex Particles. 1. Influence of Initiator Properties and Mode of Monomer Addition. Macromolecules, 27, 1932-1937.
[7] Cunningham, M.F., Mahabadi, H.K. and Wright, H.M. (2000) Supermicron Polymer Particles with Core-Shell Type Morphologies. Journal of Polymer Science, Part A: Polymer Chemistry, 38, 345-351.
[8] Oi, D.M., Bao, Y.Z., Huang, Z.M. and Weng, Z.X. (2006) Synthesis and Characterization of Poly(butyl acrylate)/Silica and Poly(butyl acrylate)/Silica/Poly(methyl methacrylate) Composite Particles. Journal of Applied Polymer Science, 99, 3425-3432.
[9] Muroi, S., Hashimoto, H. and Hosoi, K. (1984) Morphology of Core-Shell Latex Particles. Journal of Polymer Science: Polymer Chemistry Edition, 22, 1365-1372.
[10] Daniel, E.S., Dimonie, V.L., El-Aasser, M.S. and Vanderhoff, J.W. (1990) Preparation of ABS (Acrylonitrile/Buta- diene/Styrene) Latexes Using Hydroperoxide Redox Initiators. Journal of Applied Polymer Science, 41, 2463-2477.
[11] Zhao, J., Yuan, H. and Pan, Z. (1994) Grafting Mechanism in SBR-St-MMA Core-Shell Emulsion Copolymerization. Journal of Applied Polymer Science, 53, 1447-1452.
[12] El-Aasser, M.S., Hu, R., Dimonie, V.L. and Sperling, L.H. (1999) Morphology, Design and Characterization of IPN- Containing Structured Latex Particles for Damping Applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 153, 241-253.
[13] Yabu, H., Tajima, A., Higuchi, T. and Shimomura, M. (2007) Preparation of Polymer Nanoparticles by Self-Organiza- tion. Hyomen Kagaku, 28, 277-282.
[14] Han, S.H., Ma, G.H., Du, Y.Z., Omi, S. and Gu, L.X. (2003) Preparation of Hemispherical Poly(4-vinylpyridine-co- butyl acrylate)/Poly(styrene-co-butyl acrylate) Composite Microspheres by Seeded Preswelling Emulsion Polymerization. Journal of Applied Polymer Science, 90, 3811-3821.
[15] Hu, G., Yu, D., Zhang, J., Liang, H. and Cao, Z. (2011) Synthesis of Micron-Sized Poly(styrene-co-divinylbenzene) Hollow Particles from Seeded Emulsion by Using Swelling Solvents. Colloid Journal, 73, 557-564.
[16] Zhang, Q., Yang, Z., Zhan, X. and Chen, F. (2009) Preparation and Structure Control of Hollow Polymer Particles: Influence of Seeded Emulsion Polymerization and Alkalization Treatment Process. Journal of Applied Polymer Science, 113, 207-215.
[17] Okubo, M., Fujibayashi, T., Yamada, M. and Minami, H. (2005) Micron-Sized, Monodisperse, Snowman/Confetti- Shaped Polymer Particles by Seeded Dispersion Polymerization. Colloid and Polymer Science, 283, 1041-1045.
[18] Fujibayashi, T., Tanaka, T., Minami, H. and Okubo, M. (2010) Thermodynamic and Kinetic Consideration on the Morphological Stability of “Hamburger-Like” Composite Polymer Particles Prepared by Seeded Dispersion Polymerization. Colloid and Polymer Science, 288, 879-886.
[19] Okubo, M., Fujibayashi, T. and Terada, A. (2005) Synthesis of Micron-Sized, Monodisperse Polymer Particles of Disk-Like and Polyhedral Shapes by Seeded Dispersion Polymerization. Colloid and Polymer Science, 283, 793-798.
[20] Higuchi, T., Tajima, A., Motoyoshi, K., Yabu, H. and Shimomura, M. (2009) Suprapolymer Structures from Nanostructured Polymer Particles. Angewandte Chemie International Edition, 48, 5125-5128.
[21] Higuchi, T., Tajima, A., Yabu, H. and Shimomura, M. (2008) Spontaneous Formation of Polymer Nanoparticles with Inner Micro-Phase Separation Structures. Soft Matter, 4, 1302-1305.
[22] Ma, G.H., Nagai, M. and Omi, S. (1999) Study on Preparation and Morphology of Uniform Artificial Polystyrene- Poly(methyl methacrylate) Composite Microspheres by Employing the SPG (Shirasu Porous Glass) Membrane Emulsification Technique. Journal of Colloid and Interface Science, 214, 264-282.
[23] Okubo, M., Saito, N. and Fujibayashi, T. (2005) Preparation of Polystyrene/Poly(methyl methacrylate) Composite Particles Having a Dent. Colloid and Polymer Science, 283, 691-698.
[24] Saito, N., Kagari, Y. and Okubo, M. (2006) Effect of Colloidal Stabilizer on the Shape of Polystyrene/Poly(methyl methacrylate) Composite Particles Prepared in Aqueous Medium by the Solvent Evaporation Method. Langmuir, 22, 9397-9402.
[25] Ogino, K., Sato, H., Tsuchiya, K., Suzuki, H. and Moriguchi, S. (1995) Synthesis of Monodisperse Macroreticular Styrene-Divinylbenzene Gel Particles by a Single-Step Swelling and Polymerization Method. Journal of Chromatography A, 699, 59-66.

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