3D Numerical Simulation of Epidermal Skin Turnover Process Using a Particle Model

Katsuya Nagayama¹, Takahiro Uehara¹, Yasuko Amano², Masanori Tanahashi²

¹Kyushu Institute of Technology, Fukuoka, Japan.
²Kao Corporation, Tokyo, Japan.

DOI: 10.4236/jbm.2015.33007                

Abstract

Skin is the largest organ of the human body. In recent years, concern regarding the cosmetics area has increased, and research studies on anti-aging therapy or cosmetics have been rapidly conducted. Skin cells are not only changing its shape but also its physical properties during the epidermal skin turnover process. Computational simulation can be useful in further understanding the mechanisms of skin formation. We propose a particle model that can handle complex biological phenomena, including cell interactions and is a suitable method for simulating skin formation. The particle model was applied to simulate three-dimensional skin formation accompanied by proliferation and cornification of skin cells. The simulation results represented and reproduced the epidermal skin turnover phenomenon.

Keywords

Numerical Simulation, Skin Formation, Particle Model

Conflicts of Interest

The authors declare no conflicts of interest.

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