How and Why Do Gestational Trophoblastic Neoplasms Overproduce Human Chorionic Gonadotropin?

C. V. Rao^*

Departments of Cellular Biology and Pharmacology, Molecular and Human Genetics and Obstetrics and Gynecology, Reproduction and Development Program, Herbert Wertheim College of Medicine, Florida International University, Miami, USA.

DOI: 10.4236/ojog.2015.51001                

Abstract

From the published data, the present mini-review attempts to answer two fundamental questions about the gestational trophoblastic neoplasms. In addition, it extrapolates the findings to other cancers that produce small amounts of hCG and how a novel therapies could be developed.

Keywords

Human Chorionic Gonadotropin, hCG Receptors, Gestational Trophoblastic Neoplasms, hCG Biosynthesis, Choriocarcinoma Cells

Conflicts of Interest

The authors declare no conflicts of interest.

References

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