Angiodysplasia Presenting with Multiple Polypoid Lesions: An Unusual Cause of Small Bowel Obstruction

DOI: 10.4236/crcm.2014.311128   PDF   HTML   XML   3,091 Downloads   3,446 Views  


Angiodysplasia (AD), a morphologic vascular abnormality, is a common cause of gastrointestinal bleeding. We present a rare case of polypoid AD lesions. Three years after treatment for adhesive bowel obstruction, a 57-year-old man was admitted with recurrent abdominal distension, anorexia, and lower extremity edema. Computed tomography showed his dilated proximal and collapsed distal small bowel loops had disparate calibers. The transition point demonstrated mucosal enhancement and mesenteric lymphadenopathy. We observed small intestinal wall outpouching with strong mucosal enhancement and polypoid lesions dotting the dilated intestine. Intraoperative findings revealed a hard but elastic intraluminal nodule causing small bowel obstruction and the outpouching’s occurrence on the ileum’s antimesenteric border. We performed partial resection of the small intestine involving the nodule and Meckel’s diverticulum. Macroscopically, the nodule, diverticulum, and intestinal mucosa had polypoid lesions. Histopathologically, these lesions had foci within dilated thin- or thick-walled vascular channels in the submucosa, without specific histological abnormalities. These features led to a diagnosis of AD.

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Takenaka, Y. , Sasaki, T. , Miyajima, N. and Otsubo, T. (2014) Angiodysplasia Presenting with Multiple Polypoid Lesions: An Unusual Cause of Small Bowel Obstruction. Case Reports in Clinical Medicine, 3, 592-595. doi: 10.4236/crcm.2014.311128.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Sami, S.S., Al-Araji, S.A. and Ragunath, K. (2014) Review Article: Gastrointestinal Angiodysplasia—Pathogenesis, Diagnosis and Management. Alimentary Pharmacology & Therapeutics, 39, 15-34.
[2] Holleran, G., Hall, B., Hussey, M. and McNamara, D. (2013) Small Bowel Angiodysplasia and Novel Disease Associations: A Cohort Study. Scandinavian Journal of Gastroenterology, 48, 433-438.
[3] Sohal, M. and Laffan, M. (2008) Von Willebrand Disease and Angiodysplasia Responding to Atorvastatin. British Journal of Haematology, 142, 308-309.
[4] Starke, R.D., Ferraro, F., Paschalaki, K.E., Dryden, N.H., McKinnon, T.A., Sutton, R.E., Payne, E.M., Haskard, D.O., Hughes, A.D., Cutler, D.F., Laffan, M.A. and Randi, A.M. (2011) Endothelial von Willebrand Factor Regulates Angiogenesis. Blood, 117, 1071-1080.
[5] Kakushima, N., Fujishiro, M., Yahagi, N., Oka, M., Kobayashi, K., Hashimoto, T., Miyoshi, H., Moriyama, Y., Enomoto, S., Iguchi, M., Ichinose, M. and Omata, M. (2004) An Unusual Case of Polypoid Angiodysplasia. Endoscopy, 36, 379.
[6] Van Weyenberg, S.J., Van Grieken, N.C. and Van Waesberghe, J.H. (2012) Iron Deficiency after Non-Small Cell Lung Cancer. Gastroenterology, 142, e3-e4.
[7] Tan, H., Chen, H., Xu, C., Ge, Z., Gao, Y., Fang, J., Liu, W. and Xiao, S. (2012) Role of Vascular Endothelial Growth Factor in Angiodysplasia: An Interventional Study with Thalidomide. Journal of Gastroenterology and Hepatology, 27, 1094-1101.

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