Strategizing the Development of Alzheimer’s Therapeutics (Review Paper)

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DOI: 10.4236/aad.2014.33011    4,369 Downloads   5,828 Views   Citations


Alzheimer’s Disease is a complex, progressive condition with symptoms that do not reveal themselves until significant changes to neuronal morphology have already occurred. The delayed manifestation of cognitive decline makes determination of the true etiological origins difficult. As a result, identification of ideal drug targets becomes seemingly impossible. The existing treatments for Alzheimer’s Disease may temporarily suppress the rate of cognitive decline, but do little to slow or halt neuronal decay. While many believe that the current approaches to identifying a cure for the disease are too narrow-minded, focusing heavily on the physical manifestations of the diseased brain such as amyloid plaques and neurofibrillary tangles, this review asserts the status of Alzheimer’s research as rational and multi-faceted.

Cite this paper

Davis, J. and Couch, R. (2014) Strategizing the Development of Alzheimer’s Therapeutics. Advances in Alzheimer's Disease, 3, 107-127. doi: 10.4236/aad.2014.33011.

Conflicts of Interest

The authors declare no conflicts of interest.


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