Fournier’s Gangrene: Analysis of 14 Cases

Abstract

Introduction: Perineo-scrotal gangrene is a necrotizing fasciitis concerning soft parts of the genital area which necessitates a rapid, complete and multidisciplinary medical management. The aim of our study was to describe the epidemiologic, diagnostic and therapeutic aspects of Fournier’s gangrene. Patients and methods: We have carried out a retrospective study with 14 patients with Fournier’s gangrene, who were treated from January 2011 to November 2013 at the Urology A Department of Ibn Sina University Hospital, Rabat, Morocco. Results: The average age was 58 years (47 to 76 years). All patients were male. Average time (delay) between onset of infection and consultation was one week. Clinical symptomatology was dominated by edema and erythema signs, fever and pain. In most cases, skin necrosis initially affected perineo-scrotal region. 43% of patients were diabetic. 5 patients (35%) had a urethral stricture. The most common germs found were: Escherichia coli (50%), Streptococcus (22%) and Klebsiella (14%). The treatment consisted in a large debridement, associated with fluid and electrolyte replacement and parenteral broadspectrum antibiotics with drainage of urine. Orchiectomy was required in 2 patients. The average length of hospital stay was 3 weeks. 4 patients (28%) had a scrotal collection. 2 patients (14%) died from a toxic septic shock. Conclusion: Fournier’s gangrene remains, despite the multidisciplinary medical management, a serious affection associated with high mortality. Early consultation and correction of general disorders and immune deficiencies can improve its prognosis.

Share and Cite:

Asseban, M. , Kallat, A. , Mazdar, A. , Sayegh, H. , Iken, A. , Benslimane, L. and Nouini, Y. (2014) Fournier’s Gangrene: Analysis of 14 Cases. Open Journal of Urology, 4, 109-113. doi: 10.4236/oju.2014.48019.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Fournier, J.A. (1883) Gangrène foudroyante de la verge. Medicine Pratique, 4, 589-597.
[2] Schaeffer, E.M. and Schaeffer, A.J. (2007) Infections of the Urinary Tract. In: Wein, A., Ed., Campbell-Walsh Urology, Saunders Elsevier, Philadelphia, 301-303.
[3] Eke, N. (2000) Fournier’s Gangrene: A Review of 1726 Cases. British Journal of Surgery, 87, 717-728. http://dx.doi.org/10.1046/j.1365-2168.2000.01497.x
[4] Norton, K.S., Johnson, L.W., Perry, T., Perry, K.H., Sehon, J.K. and Zibari, G.B. (2002) Management of Fournier’s Gangrene: An Eleven-Year Retrospective Analysis of Early Recognition, Diagnosis, and Treatment. The American Surgeon, 68, 709-713.
[5] Biyani, C.S., Mayor, P.E. and Powell, C.S. (1995) Case Report: Fournier’s Gangrene—Roentnographic
and Sonographic Findings. Clinical Radiology, 50, 728-729. http://dx.doi.org/10.1016/S0009-9260(0
5)83323-9
[6] Morrison, D., Blaivas, M. and Lyon, M. (2005) Emergency Diagnosis of Fournier’s Gangrene with Bed-
side Ultrasound. The American Journal of Emergency Medicine, 23, 544-547. http://dx.doi.org/10.101
6/j.ajem.2004.12.010
[7] Guibal, F., Muffat-Joly, M., Terris, B., et al. (1994) Necrotizing Fasciitis. Lancet, 344, 1771.
[8] Tuncel, A., Aydin, O., Tekdogan, U., et al. (2006) Fournier’s Gangrene: Three Years of Experience with 20 Patients and Validity of the Fournier’s Gangrene Severity Index Score. European Urology, 50, 838-43. http://dx.doi.org/10.1016/j.eururo.2006.01.030
[9] Bédos, J.P. (2006) Necrotising Cutaneous Infections and Necrotizing Fasciitis: What Antibiotic Agents to Use and How? Annales Francaises d’Anesthésie et de Réanimatio, 25, 982-985.
[10] Bronder C.S., Cowey, A. and Hill, J. (2004) Delayed Stoma Formation in Fournier’s Gangrene. Colorectal Disease, 6, 518-520. http://dx.doi.org/10.1111/j.1463-1318.2004.00663.x
[11] Mindrup, S.R., Kealey, G.P. and Fallon, B. (2005) Hyperbaric Oxygen for the Treatment of Fournier’s Gangrene. The Journal of Urology, 173, 1975-1977.
[12] Sarkis, P., Farran, F., Khoury, R., Kamel, G., Nemr, E., Biajini, J. and Merheje, S. (2009) Fournier’s Gangrene: A Review of the Recent Literature. Progrès en Urologie, 19, 75-84.

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.