Analyses on Cancer Incidence and Mortality in Huai’an Area, China, 2010

Qin Zhang, Enchun Pan, Yuan He, Wei Hu, Chuang Wang

Huai’an Center for Disease Control and Prevention, Huai’an, China.

DOI: 10.4236/ojpm.2014.46059                

Abstract

Objective: The aim of this study was to investigate the cancer incidence and mortality in Huai’an area, China, 2010. Methods: On basis of the criteria of data quality from National Central Cancer Registry (NCCR), data submitted from 8 registries in Huai’an area in 2010 were checked and evaluated. Descriptive analysis included incidence and mortality stratified by areas (urban/rural), sex, age group and cancer sites. Results: The crude incidence rate was 231.17/100,000 (males 276.04/100,000, females 183.87/100,000), age-standardized incidence rate by Chinese standard population (ASIRC) was 179.53/100,000 and by World standard population (ASIRW) was 177.24/ 100,000. The incidence rates increased rapidly in people aged 40 and over, and the peak ages of incidence were at 75 - 79 (males over 85, females at 75 - 79). The cancer mortality rate was 151.26/100,000 (186.06/100,000 in males and 114.58/100,000 in females), age-standardized mortality rate by Chinese standard population (ASMRC) was 116.67/100,000 and by World standard population (ASMRW) was 115.64/100,000. The mortality rates increased rapidly after the age of 50, reaching the peak at the ages over 85 in both males and females. Esophageal, lung, gastric, liver, colorectal, breast, pancreas, lymphoma, brain and central nervous system, cervical were the most common cancer incident sites. Esophageal, lung, liver, gastric, colorectal, pancreatic, brain and central nervous system, leukemia, breast and lymphoma were the most common cancer sites of death. Conclusions: The data quality of cancer registration is improving. As cancer burden remained high and was different between urban and rural areas, prevention and control should be implemented based on practical situation.

Keywords

Cancer, Incidence, Mortality, Huai’an Area

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Parkin, D.M. (2006) The Evolution of the Population-Based Cancer Registry. Natural Reviews of Cancer, 6, 603-612. http://dx.doi.org/10.1038/nrc1948
[2]	Curado, M.P., Edwards, B., Shin, H.R., et al. (2008) Cancer Incidence in Five Continents. Vol. IX. IARC Scientific Publications No. 160, IARC, Lyon.
[3]	Ferlay, J. (2006) The IARC crg Tools Programs. IACR, Lyon. http://www.iacr.com.fr/iarccrgtools.htm
[4]	Yuan, G.J., Li, Q.W., Du, Y.X., et al. (2012) Analyses on Cancer Incidence and Mortality in Huai’an Area, China, from 2009 to 2011. Chinese-German Journal of Clinical Oncology, 11, 504-507. http://dx.doi.org/10.1007/s10330-012-1035-4
[5]	Chen, W., Zheng, R., Zhang, S., et al. (2014) Annual Report on Status of Cancer in China, 2010. Chinese Journal of Cancer Research, 26, 48-58.
[6]	Chen, W., Zheng, R., Zhang, S., et al. (2013) Report of Incidence and Mortality in China Cancer Registries, 2009. Chinese Journal of Cancer Research, 25, 10-21.
[7]	World Health Organization (2014) GLOBOCAN2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. http://globocan.iarc.fr/Default.aspx
[8]	Wu, M., Zhang, Z.F., Kampman, E., et al. (2011) Does Family History of Cancer Modify the Effects of Lifestyle Risk Factors on Esophageal Cancer? A Population-Based Case-Control Study in China. International Journal of Cancer, 128, 2147-2157. http://dx.doi.org/10.1002/ijc.25532
[9]	Wu, M., Van’t Veer, P., Zhang, Z.F., et al. (2011) A Large Proportion of Esophageal Cancer Cases and the Incidence Difference between Regions Are Attributable to Lifestyle Risk Factors in China. Cancer Letters, 308, 189-196. http://dx.doi.org/10.1016/j.canlet.2011.05.003
[10]	Wang, J.B., Fan, J.H., Liang, H., et al. (2012) Attributable Causes of Esophageal Cancer Incidence and Mortality in China. PLoS One, 7, e42281. http://dx.doi.org/10.1371/journal.pone.0042281
[11]	Liu, M., Su, M., Tian, D.P., et al. (2010) Heredity, Diet and Lifestyle as Determining Risk Factors for the Esophageal Cancer on Nanao Island in Southern China. Family Cancer, 9, 229-238. http://dx.doi.org/10.1007/s10689-009-9300-6
[12]	Wu, M., Zhao, J.K., Hu, X.S., et al. (2006) Association of Smoking, Alcohol Drinking and Dietary Factors with Esophageal Cancer in High- and Low-Risk Areas of Jiangsu Province, China. World Journal of Gastroenterology, 12, 1686-1693.