A Case Report: Cystic Clear Cell Tumor of Borderline Malignancy of the Ovary

Yuko Matsubara, Toru Fujioka, Keiichi Matsubara, Akihiro Nawa

Department of Obstetrics and Gynecology, Ehime University School of Medicine, Toon, Japan.

DOI: 10.4236/ojog.2014.47058                

Abstract

Introduction: Ovarian borderline clear cell tumor is a very rare tumor accounting for less than 1% of borderline ovarian tumors. Currently, only 30 cases of borderline clear cell tumors have been reported. This borderline ovarian clear cell tumor often arises from endometriosis. But there are no definitive guidelines for the management of endometriosis with malignant transformation due to a lack of understanding of the mechanistic details that mediate the transformation of endometriosis into ovarian cancer. Case: A 52-year-old woman (G2 P2) who periodically underwent ultraso-nography over the course of 12 years in order to follow the endometrioma present in her left ovary. The diameter of the lesion was 46 mm and it remained largely unchanged. However, a solid region within the ovarian cyst was detected. After the surgery, the final pathological diagnosis was cystic clear cell tumor of borderline malignancy. Conclusion: It reported that risk factors of malignant transformation are older age, postmenopausal status, and larger tumor diameters were associated with a higher prevalence of cancer development. But it is recommended that patients with endometriosis, regardless of patient age or tumor size, undergo careful monitoring to detect changes in growth or the formation of solid regions for as long as the lesion is present.

Keywords

Borderline Malignancy, Clear Cell Tumor, Ovary

Conflicts of Interest

The authors declare no conflicts of interest.

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