A Global Stability Analysis of a Susceptible-Infected-Removed-Prevented-Controlled Epidemic Model ()
Abstract
A mathematical model of HIV transmission dynamics is proposed and
analysed. The population is partitioned into five compartments of susceptible S(t),
Infected I(t), Removed R(t), Prevented U(t) and the Controlled W(t).
Each of the compartments comprises of cohort of individuals. Five systems of
nonlinear equations are derived to represent each of the compartments. The
general stability of the disease free equilibrium (DFE) and the endemic
equilibrium states of the linearized model are established using the linear
stability analysis (Routh-Hurwitz) method which is found to be locally asymptotically
stable when the infected individuals receive ART and use the condom. The
reproduction number is also derived using the idea of Diekmann and is found to
be strictly less than one. This means that the epidemic will die out.
Share and Cite:
Yau, M. , Ndakwo, H. and Umar, A. (2014) A Global Stability Analysis of a Susceptible-Infected-Removed-Prevented-Controlled Epidemic Model.
Applied Mathematics,
5, 1393-1399. doi:
10.4236/am.2014.510131.
Conflicts of Interest
The authors declare no conflicts of interest.
References
[1]
|
Centers for Disease Control and Prevention (1989) Perspectives in Disease Prevention and Health Promotion Condoms for Prevention of Sexually Transmitted Diseases.
|
[2]
|
Tinuola, F.R., Ayodele J.O. and Ola, T.M. (2006) HIV/AIDS in Africa and the Politics of the West. Nigerian Journal of Social Research, 1, 100-112.
|
[3]
|
Kimbir A.R. and Oduwole, H.K (2008)A Mathematical Model of HIV/AIDS Transmission Dynamics Considering Counselling and Antiretroviral Therapy. Journal of Modern Mathematics and Statistics, 2, 166-169.
|
[4]
|
Muhammad, A.Y. (2010) A Mathematical Model of HIV Transmission Dynamics Considering the Use of Antiretroviral Therapy and a Preventive Measure (Condom). M.Sc Thesis (Unpublished).
|
[5]
|
Yang H.M. and Ferreira, W.C. (1999) A Population Model Applied to HIV Transmission, Considering Protection and Treatment. IMA Journal of Mathematics Applied in Medicine and Biology, 16, 237-259.
|
[6]
|
Hethcote, H.W. (1989) Three Basic Epidemiological Models. Applied Mathematical Ecology. Springer-Verlag, Berlin, 119-144. http://dx.doi.org/10.1007/978-3-642-61317-3_5
|
[7]
|
Diekmann, O., Heesterbeek, J.P. and Metz, J.A. (1990) On the Definition and the Computation of the Basic Reproduction Ratio R0 in Models for Infectious Diseases in Heterogeneous Populations. Journal of Mathematical Biology, 28, 365-382. http://dx.doi.org/10.1007/BF00178324
|