Congenital Coronary Variants and Anomalies: Prevalence in Cardiovascular Multislice Computed Tomography Studies in a Single Center


In the era of Multislice Computed Tomography (MSCT), few studies have been dedicated to the evaluation of coronary anomalies and variants. We aim to present, describe and assess the prevalence of congenital coronary variants and anomalies (CVA) in the MSCT coronary angiographic studies performed in our department. All the MSCT coronary angiographies performed in our department, between April 1, 2007 and May 31, 2012 were reviewed. Coronary anomalies and variants were characterized and grouped according to their type: origin, course (including myocardial bridging) and distal ending. A total of 663 patients underwent a MSCT coronary evaluation during this period. A total of 84 anomalies and variants were identified in 80 individuals: 12.1% of the population (80/663). The most frequent variant was the myocardial bridging of the anterior descending artery. Four (4.7%) of the anomalies were considered malignant, corresponding to a prevalence of 0.6% (4/663) in the population. Congenital coronary anomalies and variants are relatively common. In our study, the prevalence was 12.1%, myocardial bridging being the most common. This fact may explain the higher prevalence compared to some series based on the cardiac catheterization studies. Few of these anomalies were considered malignant, with prevalence rates similar to those found in the cardiac catheterization studies.

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Oliveira, C. , Mota, P. , Basso, S. and Catarino, R. (2014) Congenital Coronary Variants and Anomalies: Prevalence in Cardiovascular Multislice Computed Tomography Studies in a Single Center. Open Journal of Radiology, 4, 163-172. doi: 10.4236/ojrad.2014.42021.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Barriales-Villa, R., Morís, C., Sanmartín, J.C., Fernández, E., Pajín, F. and Nodar, R. (2006) Registro de anomalías congénitas de las arterias coronarias con origen en el seno de Valsalva contralateral en 13 hospitales espanoles (RACES). Revista Espanola de Cardiología, 59, 620-623.
[2] Yamanaka, O. and Hobbs, R.E. (1990) Coronary Artery Anomalies in 126,595 Patients Undergoing Coronary Arteriography. Catheterization and Cardiovascular Diagnosis, 2, 28-40.
[3] Barriales-Villa, R., Morís, C., Lopez-Muniz, A., Hernandez, L.C. and San-Roman, L. (2001) Adult Congenital Anomalies of the Coronary Arteries Described over 31 Years of Angiographic Studies in the Asturias Principality: Main Angiographic and Clinical Characteristics. Revista Espanola de Cardiología, 54, 269-281.
[4] Angelini, P. (2007) Coronary Artery Anomalies: An Entity in Search of an Identity. Circulation, 115, 1296-1305.
[5] Correia, E., Ferreira, P., Rodrigues, B., Santos, L., Faria, R., Nunes, R., Pipa, J., et al. (2010) Prevalence of Anomalous Origin of Coronary Arteries: A Retrospective Study in a Portuguese Population. Revista Portuguesa de Cardiologia, 29, 221-229.
[6] Shi, H., Aschoff, A.J., Brambs, H.J. and Hoffmann, M.K.. (2004) Multislice CT Imaging of Anomalous Coronary Arteries. European Radiology, 14, 2172-2181.
[7] Schmitt, R., Froehner, S., Brunn, J., Wagner, M., Brunner, H., Cherevatyy, O., et al. (2005) Congenital Anomalies of the Coronary Arteries: Imaging with Contrast-Enhanced, Multidetector Computed Tomography. European Radiology, 15, 1110-1121.
[8] Aleman, G.B., Burgos, A., Agüero, P.M., Rodrígues, C.S., Villoslada, J.C.P. and Ezquerra, A. (2008) Normal Anatomy, Anatomical Variants, and Anomalies of the Origin and Course of the Coronary Arteries on Multislice CT. Radiología, 50, 197-206.
[9] Shriki, J.E., Shinbane, J.S., Rashid, M.A., Hindoyan, A., Withey, J.G., DeFrance, A., et al. (2012) Identifying, Characterizing, and Classifying Congenital Anomalies of the Coronary Arteries. RadioGraphics, 32, 453-468.
[10] Kim, S.Y., Seo, J.B., Do, H.H., Heo, J.N., Lee, J.S., Song, J.W., et al. (2006) Coronary Artery Anomalies: Classification and ECG-Gated Multi-Detector Row CT Findings with Angiographic Correlation. RadioGraphics, 26, 317-334.
[11] Bazzocchi, G., Romagnoli, A., Sperandio, M. and Simonetti, G. (2011) Evaluation with 64-Slice CT of the Prevalence of Coronary Artery Variants and Congenital Anomalies: A Retrospective Study of 3236 Patients. La Radiologia Medica, 116, 675-689.
[12] Cademartiri, F., La Grutta, L., Malagò, R., Alberghina, F., Meijboom, W.B., Pugliese, F., et al. (2008) Prevalence of Anatomical Variants and Coronary Anomalies in 543 Consecutive Patients Studied with 64-Slice CT Coronary Angiography. European Radiology, 18, 781-791.
[13] Rodríguez-Granillo, G.A., Rosales, M.A., Pugliese, F., Fernández-Pereira, C. and Rodríguez, A.E. (2009) Prevalence and Characteristics of Major and Minor Coronary Artery Anomalies in an Adult Population Assessed by Computed Tomography Coronary Angiography. Eurointervention, 4, 641-617.
[14] Almeida, C., Dourado, R., Machado, C., Santos, E., Pelicano, N., Pacheco, M., et al. (2012) Anomalias das artérias coronárias. Revista Portuguesa de Cardiologia, 31, 477-494.
[15] Shabestari, A.A., Akhlaghpoor, S., Tayebivaljozi, R. and Fattahi, M.F. (2012) Prevalence of Congenital Coronary Artery Anomalies and Variants in 2697 Consecutive Patients Using 64-Detector Row Coronary CT-Angiography. Iranian Journal of Radiology, 9, 111-121.
[16] Mohlenkamp, S., Hort, W., Ge, J. and Erbel, R. (2002) Update on Myocardial Bridging. Circulation, 106, 2616-2622.
[17] Angelini, P., Velasco, J.A. and Flamm, S. (2002) Coronary Anomalies Incidence, Pathophysiology, and Clinical Relevance. Circulation, 105, 2449-2454.
[18] Pinho, T., Leta, R., Carreras, F., Alomar, X. and Pons-Lladó, G. (2006) Avaliacao das Anomalias de Origem das Artérias Coronárias com Tomografia Cardíaca Computorizada. Revista Portuguesa de Cardiologia, 25, 641-645.
[19] Zhu, J., Qin, X.G., Wu, Q.Y., Xiong, W.G., Lu, C.P. and Wang, R.F. (2011) Single Coronary Artery Anomaly: The Left Main Coronary Artery Originating from the Proximal Segment of Right Coronary Artery. Chinese Medical Journal, 124, 956-995.
[20] Lipton, M.J., Barry, W.M., Obrez, I., Silverman, J.F. and Wexler, L. (1979) Isolated Single Coronary Artery: Diagnosis, Angiographic Classification, and Clinical Significance. Radiology, 130, 39-47.
[21] Khanna, A., Torigian, D.A., Ferrari, V.A., Bross, R.J. and Rosen, M.A. (2005) Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery in Adulthood on CT and MRI. AJR, 185, 326-329.

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