Schwannoma in Ascending Colon: A Rare Cause of Abdominal Pain

Ozdal Ersoy, Umit Sekmen, Suha Goksel, Hulya Hamzaoglu, Melih Paksoy

Department of Gastroenterology, Acibadem Fulya Hospital, Istanbul, Turkey.
Department of Gastroenterology, Acibadem University, Acibadem Fulya Hospital, Istanbul, Turkey.
Department of Pathology, Acibadem Maslak Hospital, Istanbul, Turkey.
Department of Surgery, Acibadem Fulya Hospital, Istanbul, Turkey.

DOI: 10.4236/crcm.2014.35069                

Abstract

Schwannoma, (also called neurilemoma, neurinoma) is a benign tumor originating from nerve sheath of the Schwann cells. They rarely occur in gastrointestinal tract. We report a rare case of colonic schwannoma in a 38-year-old woman presenting with worsening right-sided pelvic pain, discovered after laparoscopic right-colon resection performed after the detection of a atypical polypoid mass in the ascending colon. Diagnosis is confirmed by immunohistochemical staining panel.

Keywords

Schwannoma, Colon, S-100

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Inagawa, S., Hori, M., Shimazaki, J., Matsumoto, S., Ishii, H., Iitabashi, M., Adachi, S., Kawamoto, T. and Fukao, K. (2001) Solitary Schwannoma of the Colon: Report of Two Cases. Surgery Today, 31, 833-838. http://dx.doi.org/10.1007/s005950170060
[2]	Skopelitou, A., Mylonakis, E., Charchanti, A. and Kappas, A. (1998) Cellular Neurilemoma (Schwannoma) of the Descending Colon Mimicking Carcinoma. Diseases of Th Colon & Rectum, 41, 1193-1196. http://dx.doi.org/10.1007/BF02239444
[3]	Diaconescu, M.R. and Diaconescu, S. (2012) Mezenchymal (Non-Epithelial) “Non-GIST” Tumors of the Digestive Tract. Chirurgia, 107, 742-750.
[4]	Prevot, S., Bienvenu, L., Vaillant, J.C. and de Saint-Maur, P.P. (1999) Benign Schwannoma of the Digestive Tract: A Clinicopathologic and Immunohistochemical Study of Five Cases, Including a Case of Esophageal Tumor. The American Journal of Surgical Pathology, 23, 431-436. http://dx.doi.org/10.1097/00000478-199904000-00007
[5]	Goh, B.K., Chow, P.K., Kesavan, S., Yap, W.M., Ong, H.S., Song, I.C., et al. (2008) Intraabdominal Schwannomas: A Single Institution Experience. Journal of Gastrointestinal Surgery, 12, 756-760. http://dx.doi.org/10.1007/s11605-007-0441-3
[6]	Mulchandani, M.H., Chattopadhyay, D., Obafunwa, J.O. and Joypaul, V.B. (2005) Gastrointestinal Autonomic Nerve Tumors-Report of a Case and Review of the Literature. World Journal of Surgical Oncology, 3, 46. http://dx.doi.org/10.1186/1477-7819-3-46
[7]	Baek, S.J., Hwangbo, W., Kim, J. and Kim, I.S. (2013) A Case of Benign Schwannoma of the Ascending Colon Treated with Laparoscopic-Assisted Wedge Resection. International Surgery, 98, 315-318. http://dx.doi.org/10.9738/INTSURG-D-13-00015.1
[8]	Vasilakaki, T., Skafida, E., Arkoumani, E., Grammatoglou, X., Tsavari, K.K., Myoteri, D., Mavromati, E., Manoloudaki, K. and Zisis, D. (2012) Synchronous Primary Adenocarcinoma and Ancient Schwannoma in the Colon: An Unusual Case Report. Case Reports in Oncology, 5, 164-168.
[9]	Kim, H.J., Kim, C.H., Lim, S.W., Huh, J.W., Kim, Y.J. and Kim, H.R. (2012) Schwannoma of Ascending Colon Treated by Laporoscopic Right Hemicolectomy. World Journal of Surgical Oncology, 15, 81. http://dx.doi.org/10.1186/1477-7819-10-81
[10]	Cal1skan, C., Akgün, E., Doganavsargil, B. and Korkut, M.A. (2009) Rare Tumors Mimicking Colorectal Carcinomas. Ege Journal of Medicine, 48, 101-107.
[11]	Mysorekar, V.V., Rao, S.G., Jalihal, U. and Sridhar, M. (2010) Schwannoma of the Ascending Colon. Indian Journal of Pathology and Microbiology, 53, 198-200. http://dx.doi.org/10.4103/0377-4929.59241
[12]	Zheng, L., Wu, X., Kreis, M.E., Yu, Z., Feng, L., Chen, C., Xu, B., Bu, Z., Li, Z. and Ji, J. (2014) Clinicopathological and Immunohistochemical Characterisation of Gastric Schwannomas in 29 Cases. Gastroenterology Research and Practice, 2014, Article ID: 202960.
[13]	Petrie, B.A., Ho, J.M. and Tolan, A.M. (2013) Schwannoma of the Sigmoid Colon: A Rare Cause of Sigmoidorectal Intussusception. ANZ Journal of Surgery (Epub Ahead of Print). http://dx.doi.org/10.1111/ans.12364
[14]	Di Cataldo, A., Trombatore, C., Cocuzza, A., Latino, R., Li Destri, G. and Petrillo, G. (2013) Synchronous Occurrence of Colon Adenocarcinoma and Gastric Schwannoma Case Report and Review of the Literature. Annali Italiani di Chirurgia, 84 (Epub Ahead of Print).
[15]	Zippi, M., Pica, R., Cassieri, C., Avallone, E.V. and Occhigrossi, G. (2013) Schwannoma of the Rectum: A Case Report and Literature Review. World Journal of Clinical Cases, 16, 49-51. http://dx.doi.org/10.12998/wjcc.v1.i1.49
[16]	Daimaru, Y., Kido, H., Hashimoto, H. and Enjoji, M. (1988) Benign Schwannoma of the Gastrointestinal Tract: A Clinicopathologic Immunohistochemical Study. Human Pathology, 19, 257-264. http://dx.doi.org/10.1016/S0046-8177(88)80518-5
[17]	Mulchandani, M.H., Chattopadhyay, D., Obafunva, J.O. and Joypaul, V.B. (2005) Gastrointesstinal Autonomic Nerve Tumors—A Report of a Case and Review of the Literature. World Journal of Surgical Oncology, 3, 46. http://dx.doi.org/10.1186/1477-7819-3-46
[18]	Wilde, B.K., Senger, J.L. and Kanthan, R. (2010) Gastrointestinal Schwannoma: An Unusual Colonic Lesion Mimicking Adenocarcinoma. Canadian Journal of Gastroenterology, 24, 233-236.
[19]	Levy, A.D., Quiles, A.M., Miettinen, M. and Sobin, L.H. (2005) Gastrointestinal Schwannomas: CT Features with Clinicopathologic Correlation. American Journal of Roentgenology, 184, 797-802. http://dx.doi.org/10.2214/ajr.184.3.01840797
[20]	Fletcher, C.D., Berman, J.J., Corless, C., Gorstein, F., Lasota, J., Longley, B.J., et al. (2002) Diagnosis of Gastrointestinal Tumors: A Consensus Approach. Human Pathology, 33, 459-465. http://dx.doi.org/10.1053/hupa.2002.123545
[21]	Miller, R.T. (2013) Immunohistochemistry in the Differential Diagnosis of Schwannoma and Neurofibroma. www.propathlab.com